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Dictyostelium cells shown to lay 'breadcrumb trail' as first step in multicellular formation

12/1/2008
When starved of their food source and then presented with a chemoattractant signal like cAMP, individual Dictyostelium cells acquire a polarized morphology and aggregate to form a migrating stream. This is the first step in a developmental program that culminates in the formation of a multicellular organism. Kriebel et al. show how this streaming response is coordinated at a single-cell level... [Comments]

Claudin 11 stops the leaks in neuronal myelin sheaths

12/1/2008
Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit. The study will be published in the December 1, 2008 issue of the Journal of Cell Biology ( www.jcb.org ). Like the rubber coating on a copper wire, the myelin sheatha membrane extension of glial cells that spirals around the axons of neuronscreates an insulation laye... [Comments]

Prostate cancer spurs new nerves

12/1/2008
Prostate cancer and perhaps other cancers promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the journal Clinical Cancer Research . Previous research showed that prostate cancer follows the growth... [Comments]

Marked improvement in body image, physical stamina, post-surgical pectus patients report

12/1/2008
Patients who have had the common chest wall deformity known as pectus excavatum corrected report improved body image and ability to exercise, according to a study published December in the journal Pediatrics . The study, conducted at 11 North American hospitals, involved telephone interviews of more than 200 patients between the ages of 8 and 21 who had pectus excavatum surgery. Research... [Comments]

Researchers learn that some 'good cholesterol' isn't good enough

11/30/2008
If you think your levels of "good cholesterol" are good enough, a new study published in the December 2008 issue of The FASEB Journal suggests that you may want to think again. In the report, researchers from the University of Chicago challenge the conventional wisdom that simply having high levels of good cholesterol (HDL) and low levels of bad cholesterol (LDL) is necessary for good heath.... [Comments]

European ancestry increases breast cancer risk among Latinas

11/30/2008
PHILADELPHIA Latina women have a lower risk of breast cancer than European or African-American women generally, but those with higher European ancestry could be at increased risk, according to data published in the December 1 issue of Cancer Research , a journal of the American Association for Cancer Research. "We need to study the possible factors that are placing Latina women of high E... [Comments]

Persistent pollutant may promote obesity

11/30/2008
Tributyltin, a ubiquitous pollutant that has a potent effect on gene activity, could be promoting obesity, according to an article in the December issue of BioScience . The chemical is used in antifouling paints for boats, as a wood and textile preservative, and as a pesticide on high-value food crops, among many other applications. Tributyltin affects sensitive receptors in the cells of... [Comments]

BioScience tip sheet, December 2008

11/30/2008
The December 2008 issue of BioScience includes a Special Section consisting of four articles on Endocrine Disruptors in the Environment, coordinated by Louis J. Guillette, Jr., of the University of Florida. The complete list of research articles in the issue is as follows: Meeting the Challenges of Aquatic Vertebrate Ecotoxicology. Michael J. Carvan III, John P. Incardona, and Matth... [Comments]

Scientists developing food allergy treatment

11/30/2008
A team of scientists from across Europe are embarking on new research to develop a treatment for food allergy. "Food allergy affects around 10 million EU citizens and there is no cure," says Dr Clare Mills of the Institute of Food Research, a lead partner in the Food Allergy Specific Therapy (FAST) research project. "All people with food allergy can do is avoid the foods to which they are a... [Comments]

Cell movements totally modular, Stanford study shows

11/30/2008
STANFORD, Calif. A study describing how cells within blood vessel walls move en masse overturns an assumption common in the age of genomics that the proteins driving cell behavior are doing so much multitasking that it would be near impossible to group them according to a few discrete functions. But now researchers at the Stanford University School of Medicine have shown that distinct... [Comments]

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(Date:11/27/2008)...s at St. Jude Children,s Research Hospital have id... cells of children with acute lymphoblastic leukem...pathway to designing treatments for ALL relapse in... common childhood cancer, ALL affects thousands of...more than 80 percent of ALL cases are cured, relap...
(Date:11/26/2008)...ife Conservation Society, the Government of Camero... a new national park to help protect the world,s m... , The park now forms part of an important trans...r National Park, safeguarding an estimated 115 gor...along with other rare species. Trans-boundary prot...
(Date:11/26/2008)...pes societies, but it is a factor only just beginn...e Norwegian professor, writer and film maker Terje...gues that water has played a unique and fundamenta...ry. Speaking at a European Science Foundation and ...ed that social scientists and historians have long...
(Date:11/26/2008)...d by University of North Carolina at Chapel Hill r...ne changes in their brains and behavior that may m...ntially expanded after receiving an additional $3....g Study (IBIS), which involves a network of univer... by the National Institutes of Health as an Autism...
Breaking Biology News(10 mins):St. Jude identifies genomic causes of a certain type of leukemia relapse 2St. Jude identifies genomic causes of a certain type of leukemia relapse 3New national park protects world's rarest gorilla 2New national park protects world's rarest gorilla 3Using water to understand human society, from the industrial revolution to global trade 2Using water to understand human society, from the industrial revolution to global trade 3UNC expands brain imaging study of infants at risk for autism 2Active seniors curb health care costs 11920 1Active seniors curb health care costs 11920 2inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 1inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 2inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 3The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 1The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 2The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 3Newly Released 2009 COLA Forecast Would Keep Five Million Seniors Below Poverty Line 11914 1Newly Released 2009 COLA Forecast Would Keep Five Million Seniors Below Poverty Line 11914 2
...predict will do more harm than simply raise the se...astic changes in fragile ecosystems throughout the...trend during the last few decades in the Antarctic...to migrate south and perhaps diminished the abunda...ood chain at the bottom of the world. , "We,re...
...ood cell types may help physicians accurately dist...mononucleosis and bacterial tonsillitis, potential...ticle in the January issue of Archives of Otolaryn...chives journals. , Acute tonsillitis (inflammation...sed by the Epstein-Barr virus) are both common ear...
...netic malfunction that causes a form of mental ret...mbalance in the genesis of two types of cells in t...y theorize, could explain how the genetic abnormal...rder. More broadly, they said, the new insight int... inherited forms of retardation. , Freda Miller of...
... could be an inexpensive alternative to current me...anders Interuniversity Institute for Biotechnology...cing in plant seeds proteins that have a very stro...strated that these antibody variants are just as a... in humans. By virtue of their particular action, ...
Other Biology News:Antarctic warming to reduce animals at base of ecosystem, shift some penguin populations southward 2Common blood test can help distinguish between mononucleosis and tonsillitis 2How genetic malfunction causes a form of retardation 2Producing medicines in plant seeds 2Producing medicines in plant seeds 3
...177 amino acid polypeptide sequence corresponding ...d by activation of a recombinant soluble proform o...IC ACTIVITY:The specific activity of MT1-MMP catal...ity that hydrolyzes 1 mol peptide (7-methoxycoumar...
Human interferon-beta (IFN-beta). Recognizes amino acids 30-47 of IFN-beta. No cross-reactivity with Human IFN-alpha or IFN-gamma.
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(Date:11/27/2008)...itzerland, November 27 Helsinn Hea...has signed a partnering agreement with,Zealand Ph...ization of,ZP1846, a GLP-2 (glucagon-like peptide...o treat chemotherapy-induced diarrhea (CID), a deb... cancer treatment with a range of,chemotherapies....
(Date:11/26/2008)...exterior of your house always looking good, withou...is now possible with paint that can maintain itsel... A process for producing photo-catalytic, self-cle... Singapore,s A*STAR (Agency for Science, Technolog...d. , The patented process produces a coating con...
(Date:11/26/2008)...s wins increase 400% to $16 million in third quart... include $1.9 million non-cash goodwill impairment...e-FirstCall/ -- Encorium Group, Inc. (Nasdaq: E...arch organization (CRO) conducting studies in over...rmaceutical and biotechnology companies, today ann...
(Date:11/26/2008)...srael and JERSEY CITY, New Jersey, November 26,/P... ROSG ), today announced it,will release third q...re the,U.S. markets open. Rosetta Genomics will h... to discuss these results at 8:30 a.m. ET on Frida...ence call, U.S. and Canadian participants may,dia...
Breaking Biology Technology:Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist 2Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist 3Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist 4Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist 5Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist 6Photo-catalytic, self cleaning coating for building exteriors 2Photo-catalytic, self cleaning coating for building exteriors 3Photo-catalytic, self cleaning coating for building exteriors 4Encorium Reports Third Quarter 2008 Financial Results 2Encorium Reports Third Quarter 2008 Financial Results 3Encorium Reports Third Quarter 2008 Financial Results 4Encorium Reports Third Quarter 2008 Financial Results 5Encorium Reports Third Quarter 2008 Financial Results 6Encorium Reports Third Quarter 2008 Financial Results 7Encorium Reports Third Quarter 2008 Financial Results 8Encorium Reports Third Quarter 2008 Financial Results 9Rosetta Genomics Announces Conference Call and Webcast of Third Quarter Financial Results 2
...s column, I have become aware of a lot of life sci...idwest. Part of the challenge of this column has b...ough many Midwest life science companies are well ... radar screen of awareness. Rarely, however, has b...any (particularly a publicly traded company). , ,A...
...-year-old conference draws nearly 1,000 people fro...r of technology. As the lead speaker on a two-hour...ic and Social Conditions, I was eager, frankly, to...ndicators in order to hear from and debate my fell...onal and corporate time a very un-French concept....
...-profit arm the SBC Foundation, has given $285,500...fits, the Business Journal of Milwaukee has repor...cial services to at-risk youth and underserved pop...nology. The grants were part of SBC,s Excelerator...5,000 per organization. , ,Ten of the 24 grants, t...
...e the Madison chapter of the World Future Society...social and technological developments, Scott Conve...e important if they want to see where the next big... technology director at the UW-Madison School of B...nt Dance Technologies, spoke to the society on Thu...
Other Biology Technology:Bio-Logic Systems, another Midwest life-science firm, flies under the radar 2Bio-Logic Systems, another Midwest life-science firm, flies under the radar 3Bio-Logic Systems, another Midwest life-science firm, flies under the radar 4Achieving digital solidarity 2Achieving digital solidarity 3Achieving digital solidarity 4Business-school IT director points to reasons for wireless trend 2