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Affymetrix


Affymetrix chips are oligos synthesized on the chip. The synthesis process (lithographic process) is controlled by a set of maskers. A unique aspect of Affymetrix chip is its use of multiple "match" and "mismatch" oligos for each gene (feature).
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Robert Lipshutz (Affymetrix) discussed applications of high-density oligonucleotide arrays (DNA probe arrays) to screen and physically map cosmid clones into contigs and to detect mutations for clinical diagnosis.
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the Affymetrix GeneChip arrays, glycosyltransferases are not adequately represented, which makes comprehensive surveys of their gene expression difficult.
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