HOME >> BIOLOGY >> NEWS
$14 Million NIH grant launches heart, lung, blood and sleep disorders center at the Jackson Laboratory

Bar Harbor, Maine: Cracking the genetic codes controlling the vital physical functions of breathing, circulation, blood formation and sleep is now on the horizon. Taking advantage of new technologies and the similarity between the human and mouse genomes, the National Institutes of Health has made a four-year, $14 million grant to The Jackson Laboratory to establish a center for mouse models of heart, lung, blood and sleep disorders.

The center has two key goals: (1) developing new models and databases for biomedical researchers worldwide, and (2) advancing understanding of the genetic mechanisms underlying healthy function and diseases of the heart, lungs and blood, as well as the physiology of sleep. Dr. Luanne L. Peters, a Jackson Laboratory staff scientist, is the new centers program director. "Mice and humans share a remarkably similar genome, and get many of the same diseases, including atherosclerosis, hyperactive airways, and high blood pressure," Dr. Peters explains. "At The Jackson Laboratory, our knowledge of the mouse genome makes it possible for us to analyze complex human diseases, using powerful new genetic and molecular techniques to identify genes and track their interactions."

In the past, finding new mouse models of heart, lung, blood and sleep disorders has been difficult because many of these conditionshypertension, for exampledo not present an overt phenotype (i.e., show visible characteristics).

Also, though the human genome has been sequenced and the mouse genome is close to completion, a great deal still needs to be learned about how individual genes work and how multiple genes interact to cause complex diseases such as atherosclerosis and thrombosis. "Its estimated that humans and mice have up to 100,000 genes," Dr. Peters says, "but we know the function of fewer than 10% of them."

The Jackson Laboratory program is designed to address both problems using a "phenotype-driven" approach. "Well start out by studying some of
'"/>

Contact: Joyce Peterson
joyce@jax.org
207-288-6051
Jackson Laboratory
3-Oct-2000


Page: 1 2

Related biology news :

1. $7.5 Million grant to Yale researchers for role of viruses in cancer
2. K-States National Agricultural Biosecurity Center receives $1.3 Million from Department of Defense
3. 5 Million award for pioneering project to train new breed of scientists
4. 2 Million of yeast to triple available drug treatments
5. $10 Million center for theoretical biological physics created at UCSD by NSF
6. Million dollar grant by the Paul G. Allen Foundation for Medical Research to University of Washington medical scientist program
7. NSF awards $4.2 Million grants to three coastal sites for long-term ecological research
8. JDF awards $10 Million to Childrens Hospital of Pittsburgh and University of Pittsburgh for new research center to help speed diabetes cure
9. AVAX Technologies receives an additional $3.0 Million (AUD) investment in Australian joint venture from Australian Vaccine Technologies Ltd.
10. Columbia University College of Physicians and Surgeons receives $2.4 Million grant from Howard Hughes Medical Institute
11. UCSF School of Medicine receives $3.8 Million grant for biomedical research

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/22/2018)... ... December 21, 2018 , ... ... and hosted the Boston Healthcare Drinks event featuring Helen Chen, Greater China Managing ... China.” , The discussion was moderated by patent attorney David J. Dykeman ...
(Date:12/19/2018)... (PRWEB) , ... December 19, 2018 , ... InTouchMD’s flagship ... innovative products in healthcare for 2018. , PM360 is featuring the recognition in ... products and services offered to the pharmaceutical and medical device industries. , “This ...
(Date:12/18/2018)... ... December 18, 2018 , ... ... cancers and other serious diseases, today announced the publication of an early feasibility ... treatment of rGBM. , The publication of the study, An Early Feasibility ...
Breaking Biology News(10 mins):
(Date:1/7/2019)... ... January 07, 2019 , ... Kainos Medicine Inc. today announced ... candidate, code-named "KM-819." KM-819 is an orally active small molecule that is ... Korea. , This Phase 1 randomized, double-blind, placebo-controlled dose-escalation study was to ...
(Date:12/20/2018)... ... December 20, 2018 , ... New Year’s brings reflection and desire to improve ... the European Union (EU) on the horizon, Jim Kasic, president and CEO of Boulder ... the EU Medical Device Regulation (MDR), digital health, and big data are just a ...
(Date:12/18/2018)... ... ... Patients with early stages of breast cancer who undergo partial breast proton ... irradiation, a new study suggests. , Patients with early stage breast cancer — stage ... the cancerous tumor because there is a 30 to 40 percent change the disease ...
(Date:12/13/2018)... ... December 13, 2018 , ... Microbial Discovery Group LLC (MDG) ... been part of their strategic plan and an important milestone in increasing their ... opportunities for MDG within the $44 Billion human probiotic market. This plan is ...
Breaking Biology Technology:
Cached News: