$6.75 Million to extend primate studies of diet and aging

MADISON - A decade-long study of how diet affects the process of growing old, will continue and be expanded at the University of Wisconsin-Madison with the help of $6.75 million from the National Institutes of Health (NIH).

Begun in 1989 at the Wisconsin Regional Primate Research Center (WRPRC), the study of rhesus macaques on controlled diets is one of only two such studies in the world. The research, according to Richard Weindruch, a UW-Madison Medical School professor and the lead scientist for the project, is intended to answer a central question of biology: Can aging be held at bay by cutting down on calories?

"Dietary restriction offers a powerful experimental strategy to explore mechanisms of aging because it is the only intervention which has repeatedly and strongly increased maximum life span and retarded the rate of aging in laboratory rodents," said Weindruch. "But the study of calorie restriction and aging in non-human primates is in its infancy, as compared to the body of work done in rodents."

The new grant will enable scientists to continue studies in rhesus macaques, a much-studied and long-lived animal whose genetic and physiological characteristics parallel those of humans. The work is being conducted in several groups of primates whose calorie intake for the past five to 10 years has been reduced by about 30 percent, as well as monkeys whose diets permit them to eat as much as they wish.

The study of rhesus monkeys builds on extensive research in rodents, spiders and other animals that shows life span can be significantly extended and the rate of aging slowed by maintaining a nutritious but restricted diet, according to Weindruch.

In the ongoing Wisconsin study, the influence of diet on aging is tracked by monitoring and measuring a set of biological functions, known as biomarkers of aging, that tend to change as animals and people grow older (see sidebar).

Over the past decade, the Wisconsin study has provided a wealth

Contact: Richard Weindruch
University of Wisconsin-Madison

Page: 1 2 3

Related biology news :

1. $7.5 Million grant to Yale researchers for role of viruses in cancer
2. K-States National Agricultural Biosecurity Center receives $1.3 Million from Department of Defense
3. 5 Million award for pioneering project to train new breed of scientists
4. 2 Million of yeast to triple available drug treatments
5. $10 Million center for theoretical biological physics created at UCSD by NSF
6. Million dollar grant by the Paul G. Allen Foundation for Medical Research to University of Washington medical scientist program
7. $14 Million NIH grant launches heart, lung, blood and sleep disorders center at the Jackson Laboratory
8. NSF awards $4.2 Million grants to three coastal sites for long-term ecological research
9. JDF awards $10 Million to Childrens Hospital of Pittsburgh and University of Pittsburgh for new research center to help speed diabetes cure
10. AVAX Technologies receives an additional $3.0 Million (AUD) investment in Australian joint venture from Australian Vaccine Technologies Ltd.
11. Columbia University College of Physicians and Surgeons receives $2.4 Million grant from Howard Hughes Medical Institute

Post Your Comments:

(Date:6/23/2020)... ... June 23, 2020 , ... ... services, today announced that the company has received ISO9001:2015 certification for the ... and research industries. The decision to pursue ISO9001 accreditation demonstrates Kemp’s commitment ...
(Date:6/19/2020)... ... , ... The director of stem cell biotechnology company Asymmetrex , Dr. ... pharmaceutical industries have easier access to stem cell counting, they will soon make it ... Independence Day weekend in the U.S., Asymmetrex is offering free tissue stem cell counting ...
(Date:6/11/2020)... ... 2020 , ... Superior Controls, Inc. , an E Technologies Company and ... life sciences industry, is pleased to announce the recent hiring of Ray Boudreau, who ... New Hampshire office. In his new role, Boudreau will use his extensive experience ...
Breaking Biology News(10 mins):
(Date:6/23/2020)... ... 2020 , ... Kerafast Inc. , developers of an ... availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The system, developed ... viral entry and COVID-19 vaccine effectiveness at just biosafety level 2 (BSL-2) containment. ...
(Date:6/23/2020)... ... 2020 , ... Dracen Pharmaceuticals Inc., announced today that two ... the American Association for Cancer Research Virtual meeting. One poster describes the immuno-metabolism ... agent activity in KEAP1 mutant tumor models of NSCLC. , “As ...
(Date:6/11/2020)... ... , ... Greffex, a leading genetic engineering company, with the ... vectors, recently announced a key manufacturing agreement with FUJIFILM Diosynth Biotechnologies to produce ... successful gene therapy delivery vehicle (vector) with broad applications for delivering treatments including ...
(Date:6/11/2020)... ... June 09, 2020 , ... Reducing carbon emissions has ... From the Paris Agreement to stock market dips, ways to reduce CO2 is something ... to their portfolio. Most of the biofuels being produced today are created from recycled ...
Breaking Biology Technology:
Cached News: