$7.5 Million grant to Yale researchers for role of viruses in cancer

New Haven, Conn. -- The National Cancer Institute recently awarded a five-year, $7.5 million program project grant to investigators at the Yale School of Medicine to continue studies on the role of viruses and mutant cellular proteins in tumorigenic transformation of cells.

This grant, "Program on the Molecular Basis of Viral and Cellular Transformation," is currently in its 31st year and is one of the largest and longest-running basic science grants at Yale. It coordinates studies to understand how viral genes and related cellular genes cause cells to escape normal growth controls and induce cancer.

"Because viruses are so well-defined and relatively simple compared to their host cells, we are optimistic that studies supported by this grant will continue to identify new targets for therapy and suggest new approaches to prevent and treat cancers," said principal investigator Daniel DiMaio, M.D., Waldemar Von Zedtwitz Professor of Genetics and vice chair of the Department of Genetics.

DiMaio studies human papillomaviruses (HPV), the causative agents of cervical cancer. His laboratory has shown that HPV oncogenes must be expressed continuously in cervical cancer cells for the cells to maintain their malignant characteristics, validating the viral genes as new therapeutic targets. In the current granting period, the DiMaio laboratory will continue to dissect the pathways activated when HPV oncogenes are repressed in cervical cancer cells.

Epstein-Barr Virus and Kaposi's Sarcoma Herpesvirus, two herpesviruses that are unusual in their ability

Contact: Janet Rettig Emanuel
Yale University

Page: 1 2

Related biology news :

1. K-States National Agricultural Biosecurity Center receives $1.3 Million from Department of Defense
2. 5 Million award for pioneering project to train new breed of scientists
3. 2 Million of yeast to triple available drug treatments
4. $10 Million center for theoretical biological physics created at UCSD by NSF
5. Million dollar grant by the Paul G. Allen Foundation for Medical Research to University of Washington medical scientist program
6. $14 Million NIH grant launches heart, lung, blood and sleep disorders center at the Jackson Laboratory
7. NSF awards $4.2 Million grants to three coastal sites for long-term ecological research
8. JDF awards $10 Million to Childrens Hospital of Pittsburgh and University of Pittsburgh for new research center to help speed diabetes cure
9. AVAX Technologies receives an additional $3.0 Million (AUD) investment in Australian joint venture from Australian Vaccine Technologies Ltd.
10. Columbia University College of Physicians and Surgeons receives $2.4 Million grant from Howard Hughes Medical Institute
11. UCSF School of Medicine receives $3.8 Million grant for biomedical research

Post Your Comments:

(Date:4/6/2017)... , April 6, 2017 Forecasts ... ANPR, Document Readers, by End-Use (Transportation & Logistics, Government ... Oil, Gas & Fossil Generation Facility, Nuclear Power), Industrial, ... Other) Are you looking for a definitive ... ...
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... to expand at a CAGR of 25.76% during the ... is the primary factor for the growth of the ... https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global stem ... technology, application, and geography. The stem cell market of ...
(Date:3/30/2017)... ANGELES , March 30, 2017  On April ... Hack the Genome hackathon at Microsoft,s ... exciting two-day competition will focus on developing health and ... Hack the Genome is the ... been tremendous. The world,s largest companies in the genomics, ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... Parks Associates announced today that Tom Kerber , Director ... , October 11 in Scottsdale, Arizona . Kerber will ... safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and the introduction of ...
(Date:10/9/2017)...  BioTech Holdings announced today identification and patenting ... stem cell therapy prevents limb loss in animal ... that treatment with ProCell resulted in more than ... to standard bone marrow stem cell administration.  Interestingly, ... of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... ... in the medical journal, Epilepsia, Brain Sentinel’s SPEAC® System which uses the ... in detecting generalized tonic-clonic seizures (GTCS) using surface electromyography (sEMG). The prospective ...
(Date:10/6/2017)... ... October 06, 2017 , ... The HealthTech Venture Network (HTVN) ... their fourth annual Conference where founders, investors, innovative practitioners and collaborators are invited ... competition showcasing early stage digital health and med tech companies. , This day-long ...
Breaking Biology Technology:
Cached News: