15 Drugs, Dyes And Other Chemicals Newly Listed As Known Or Likely Human Carcinogens


Newly listed as known human carcinogens:

CYCLOSPORIN, an immunosuppressive drug.

THIOTEPA, a drug used to treat lymphomas and tumors of the breast and ovary. It has also been used at high doses in combination chemotherapy with cyclophosphamide in patients with refractory malignancies treated with autologous bone transplantation.

Newly listed as Reasonably Anticipated to be Human Carcinogens:

AZACITIDINE, a drug used to treat acute leukemia.

p-CHLORO-o-TOLUIDINE and its HC1 salt, used to produce azo dyes for cotton, silk acetate and nylon and as intermediate in production of Pigment Red 7 and Pigment Yellow 49. Also an impurity in and metabolite of the pesticide chlordimeform.

CHLOROZOTOCIN, a drug used to treat cancers of the stomach, large intestine, pancreas and lung; melanoma; and multiple myeloma.

DANTHRON, or dantron, a laxative removed from the market several years ago when tests were published indicating it caused cancer in laboratory animals. It is also an intermediate in the manufacture of dyes.

1,6-DINITROPYRENE. No commercial uses but is detected in ambient atmospheric samples and as a constituent of diesel exhaust.

1,8-DINITROPYRENE. Also in diesel exhaust and air samples.

DISPERSE BLUE 1, used as an anthraquinone-based dyestuff in several semi-permanent hair dyes and also in coloring fabrics and plastics

FURAN, used as a chemical intermediate in the synthesis and production of other organic compounds.

O-NITROANISOLE, used as a precursor in the synthesis of o-anisidine which is used in the manufacture of more than 100 azo dyes.

6-NITROCHRYSENE. Not used commercially, but detected in ambient atmospheric samples.

1-NITROPYRENE. Not used commercially, detected in ambient atmospheric samples and as a constituent of diesel exhaust.

4-NITROPYRENE. Not used commercially, detected in ambient atmospheric samples.

1,2,3-TRICHLOROPROPANE, used as a polymer crosslinking

Contact: Sandy Lange
(919) 541-0530
NIH/National Institute of Environmental Health Sciences

Page: 1 2 3

Related biology news :

1. Drugs, electronics, and green catalysts: The chemical year in review
2. Other highlights in the September 1 JNCI
3. Other highlights in the August 18 JNCI
4. Other highlights in the August 4 JNCI
5. Other highlights in the July 7 JNCI
6. Other highlights in the June 16 JNCI
7. Other Highlights in the June 2 JNCI
8. Other highlights in the May 19 JNCI
9. Other highlights in the May 5 JNCI
10. Other highlights of the March 17 issue of JNCI
11. Other highlights in the March 3 issue of JNCI

Post Your Comments:

(Date:6/1/2019)... ... May 31, 2019 , ... ... & Rosati recently invested in BioFactura’s $6M Series B Financing Round. , ... value-added institutional investors who bring significant financial and business resources to bear as ...
(Date:5/31/2019)... ... May 30, 2019 , ... Join Julie ... live webinar on Wednesday, June 19, 2019 at 1pm EDT where she ... teams, data management teams and contract research organizations (CROs) can improve collaboration, auditing, ...
(Date:5/26/2019)... ... May 24, 2019 , ... Zolgensma (Novartis, AveXis), an ... was approved for clinical use in the United States by the Food and Drug ... therapy approved to treat inherited genetic disorders in the United States and the second-ever ...
Breaking Biology News(10 mins):
(Date:5/14/2019)... ... May 13, 2019 , ... ... testing instruments for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is ... redesigned website aims to improve LDA’s ability to communicate directly with the marketplace; ...
(Date:5/7/2019)... ... May 06, 2019 , ... ... the growing number of repositories being asked to store cellular products being ... team of contributors who are world leaders, who have shared their expertise in ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... REPROCELL USA Inc. has demonstrated its ability to provide various services and ... to enhance customer satisfaction through the effective implementation of its quality management ...
(Date:5/2/2019)... Calif. (PRWEB) , ... May 02, 2019 , ... ... clinical genetics testing company, will present results documenting discrepancies between U.S. insurer policies ... guidelines for patients at risk for hereditary breast and ovarian cancer (HBOC). ...
Breaking Biology Technology:
Cached News: