Adrienne Visocchi, et al. (McMaster University, Hamilton, Canada)
The effect of isometric arm or leg exercise on resting blood pressure and arterial distensibility in persons medicated for hypertension.
Isometric handgrip (IHG) exercise seems to significantly reduce systolic blood pressure and carotid arterial distensibility.
Cheri L.M. McGowan, et al. (McMaster University, Hamilton, Canada)
IHG training improves blood pressure and endothelial function in persons medicated for hypertension.
Reduced reactive hyperemic flow, accompanied by improvements in normalized flow mediated dilation suggests a heightened vasoactive sensitivity to the reactive hyperemic stimulus, implicating it as a mechanism for improved cardiovascular function.
Thomas J. Hawke (York University, Toronto, Canada)
Molecular mechanisms of skeletal muscle regeneration.
Completion of the Human Genome Project and advent of microarray and proteomics technologies should facilitate an expanded analysis of the complex processes that regulate the myogenic progenitor cell and characterize the discrete stages of the muscle repair process.
Natasha Frank, et al. (Children's Hospital Boston, Mass.)
Expression of early developmental genes by human fetal skeletal muscle side population cells.
Early developmental mechanisms may be preserved in later stages of muscle cell commitment and differentiation and are likely to be involved in maintaining muscle side population cells in an undifferentiated state and available on demand for muscle regeneration.
Bente Klarlund Pedersen (University of Cope