HOME >> BIOLOGY >> NEWS
18F-FDG PET predicts lymphoma treatment outcome

Reston, Virginia -- A new and somewhat controversial study published in the August issue of the Journal of Nuclear Medicine suggests that 18F-FDG PET results obtained after the first cycle of treatment can better predict progression-free survival in patients with aggressive non-Hodgkin's lymphoma (NHL) or Hodgkin's disease (HD) than PET scans conducted at the end of treatment.

Physicians at the Weill Medical College of Cornell and the New York Presbyterian Hospital in New York reported on 23 patients who received PET scans before and after one cycle of treatment and also at the completion of chemotherapy. PET was accurate 87% of the time after one cycle but only 70% of the time after completion of chemotherapy. Sensitivity, i.e., the ability to detect the FDG and hence disease, was also significantly higher after one cycle, at 82% v. 45.5%. In particular, in cases in which results from the first cycle differed from the results following completion of therapy, the results from the first cycle scan were more accurate. Ninety percent of patients with positive 18F-FDG PET results after one cycle experienced disease relapse, while 85% who had negative 18F-FDG PET findings after one cycle remained in remission. The authors concluded that PET was a better predictor of outcome and response to therapy after just one cycle of chemotherapy than after completion.

PET stands for positron emission tomography. Because of its unique ability to measure metabolic activityor the efficiency of the cells converting food to energy--PET provides accurate, noninvasive detection and staging of many cancers. A radiopharmaceutical, such as 18F-FDG (fluorodeoxyglucose), which includes a radionuclide (a radioactive element) is injected into the patient and gives off signals that are measured by a PET scanner. Because cancer cells are more metabolically active, they show up on the PET images more intensely than normal tissue.

Using 18F-FDG PET to predict outco
'"/>

Contact: Karen Lubieniecki
karenlub@aol.com
703-683-0357
Society of Nuclear Medicine
5-Aug-2002


Page: 1 2 3

Related biology news :

1. Hardy buoys: Texas A&M project predicts oil spill movements
2. New tool predicts how long pollutants will stay in soil
3. Molecular marker predicts success of breast cancer treatment
4. Is that plant a tortoise or a hare? Answer predicts its response to environmental change
5. Brain signal predicts working memory prowess
6. New software developed at Rensselaer predicts promising ingredients for new drugs
7. Immunity gene predicts severe adverse drug reaction
8. New map predicts where wolves will attack
9. Study predicts conditions for sustainable lion trophy hunting
10. Inflammation marker predicts colon cancer
11. Doppler ultrasound predicts risk of miscarriage

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: FDG PET predicts lymphoma treatment outcome

(Date:11/7/2014)...  In conjunction with the Glendale ... Foundation of the Verdugos has announced the " GLENDALE ... $250,000 initiative to keep the Verdugo Regional Crime Lab operational ... months of existence, the Lab has processed more than 400 ... enforcement. "Because our number one priority is the ...
(Date:11/6/2014)... - Insilico Medicine, Inc, a Baltimore-based bioinformatics company ... diseases announced a research collaboration with the international ... Inc (OTC: CSBR). , "There are many companies ... Champions Oncology,s TumorGraft technology is unique in a ... experimentally generating vast amounts of valuable data. Our ...
(Date:11/4/2014)... of death at the right time might actually help ... that could help in understanding animal populations, pest control ... paper in the journal Trends in Ecology and ... conclude that the kind of positive population effect an ... mortality, depends on the size and developmental stage of ...
Breaking Biology News(10 mins):Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2When less is more: Death in moderation boosts population density in nature 2
(Date:11/24/2014)... , November 24, 2014 Senior ... honored for dynamic leadership skills, business acumen ... and medical information products and services, congratulates Diane ... Clinical Reference and Workflow, Elsevier Clinical Solutions, for being ... Watching ® Awards issue of Profiles in ...
(Date:11/22/2014)... Denver, Colo. (PRWEB) November 21, 2014 ... of proprietary cloud based analytics and scientific testing methodologies ... a commitment for a $750,000 line of credit from ... are extremely pleased to have secured this commitment from ... Chief Executive Officer of CannLabs. “This capital will help ...
(Date:11/22/2014)... LONDON , Nov. 21, 2014  The element ... in emerging diseases, i.e., they strike without warning. Until ... advance warning of a viral outbreak, resulting in suboptimal ... to Ebola currently. Photo - ... surprise has now been removed because virus gene structural ...
(Date:11/21/2014)... (PRWEB) November 20, 2014 Offering a ... Sartorius Entris Balance promotion . The Sartorius Entris ... a durable, high accuracy, and easy-to-maintain balance entry level ... Germany. It was designed to help customer’s bridge the ... a balance that is very durable. Sartorius is the ...
Breaking Biology Technology:Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 3CannLabs Secures $750,000 Line Of Credit 2Viruses' Advantage of Surprise is Lost 2Pipette.com Announces an Extension on the Sartorius Entris Balance Promotion to the End of 2014 2
Cached News: