A sharper look at the brain

Thanks to a dramatic improvement in imaging techniques it is now possible to generate high-resolution pictures of the monkey brain in a quality never seen before. A research group led by neurophysiologist Prof. Nikos Logothetis of the Max Planck Institute for Biological Cybernetics and physician Prof. Dr. Heinz Guggenberger of the Eberhard Karl University (both in Tübingen, Germany) was the first ever to successfully use the so-called fMRI technique (from functional magnetic resonance imaging) to produce detailed pictures of active brain regions in monkeys which have been anesthetized but are still capable of perception (nature neuroscience, Vol. 2, No. 6, June 1999). Until now, many scientists were convinced that it would be impossible to gather such images from anesthetized monkeys.

The fMRI technique uses a strong magnetic field to detect brain regions which are active and thus more strongly perfused. It promises new impetus for the area of brain research. fMRI makes it possible to pinpoint the precise regions of the monkey's visual cortex (that region of the cerebral cortex responsible for sight) where optical stimuli are processed. The non-invasive measurements are carried out under anesthesia conditions that meet the most up-to-date standards in human clinical medicine. The eyelids are held open artificially so the animals can see the presented test pattern. At the same time, constant irrigation prevents any damage to the eyes. The monkey wakes up and is fully conscious an average of 15 minutes after the experiment. The new technique places much less strain on the animal than conventional methods and makes it unnecessary to put them to sleep after the experiment.

The improved method made it possible to visualize brain volumes as small as 0.5 microliters in anesthetized monkeys and 2 microliters in a control group of alert monkeys. (One microliter is one millionth of a liter.) This is the highest resolution ever achieved in pictures of the pri

Contact: Nikos K. Logothetis

Page: 1 2 3

Related biology news :

1. Gene chips bring new order to lung cancer types, could yield sharper diagnoses, better drugs
2. Trial shows which brain cancer patients benefit from temozolomide
3. Targeted therapy knocks out pediatric brain cancer in mice
4. New way to protect brain from stroke damage
5. Chemical signals health of brain cells Symposium
6. DHA-rich diet protects brain from Alzheimers damage, UCLA study shows
7. Decreasing toxins in brains of Alzheimers patients keep cognitive deficits at bay
8. Genetic clues found for common congenital brain disorder
9. Marijuana ingredient inhibits VEGF pathway required for brain tumor blood vessels
10. Molecular therapeutics advance fight against brain cancer
11. Depression traced to overactive brain circuit

Post Your Comments:

(Date:10/8/2015)... , 8. Oktober 2015 Die ... tätiges Unternehmen des Bereiches Tracking, hat heute ... der Gefängnisbehörde Virginias (Department of Corrections – ... Überwachungsdienste für alle Strafen geliefert werden, die ... , Präsident für den Amerikanischen Kontinent der ...
(Date:10/7/2015)... Connecticut , October 7, 2015 ... authentication company focused on the growing mobile commerce market ... Stanley E. Washington , former long- term executive ... of Directors. --> NXTD ) ("NXT-ID" or ... growing mobile commerce market and creator of the Wocket® ...
(Date:10/5/2015)... http://soundview.co ) releases ... (NASDAQ: NXTD ), a biometric authentication company focused ... http://soundview.co ) releases the following market and ... a biometric authentication company focused on the growing mobile ... http://soundview.co ) releases the following market and ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... 12 de octubre de 2015 El 8 ... a un récord en el congreso con su declaración ... la International Plasma Awareness Week (IPAW), que se celebrará ... patrocinada por la Plasma Protein Therapeutics Association ... , Aumentar la concienciación mundial acerca de ...
(Date:10/12/2015)... Oct. 12, 2015  Patara Pharma, a clinical-stage ... inflammatory diseases and conditions, today announced the closing ... financing. Concurrent with the close of its sale ... Loan and Security Agreement with Silicon Valley Bank ... million. Patara will use the funds from the ...
(Date:10/12/2015)... , October 12, 2015 DorlandsOnline.com ... print version for enriched online experience --> ... alternative to print version for enriched online experience ... multi media alternative to print version for enriched ... provider of scientific, technical and medical information products and ...
(Date:10/12/2015)... (PRWEB) , ... October 12, 2015 , ... ... today that Dr. Srini Srinivasan, has joined the firm as a Premier Expert ... professional stature enable them to bring extraordinary value to the company's clients. ...
Breaking Biology Technology:
Cached News: