HOME >> BIOLOGY >> NEWS
AIDS drug helps to keep HBV at bay during chemotherapy for breast cancer

Hamburg, Germany: Researchers in Hong Kong have discovered a way to help prevent the reactivation of the hepatitis B virus in women who are being treated with chemotherapy for breast cancer.

Dr Winnie Yeo told the 4th European Breast Cancer Conference in Hamburg: "In several developing countries, as many as twelve per cent of breast cancer patients carry the hepatitis B virus. These patients are at risk of developing HBV reactivation during chemotherapy, which is a well-known complication resulting in varying degrees of liver damage that may lead to death."*

Chemotherapy suppresses the immune system and therefore allows the virus to replicate. Once chemotherapy stops, the immune system recovers and attempts to clear the virus and this causes the biochemical flare-up of hepatitis.

However, Dr Yeo has found that the anti-viral drug lamivudine can reduce the risk of HBV reactivation during and after chemotherapy. Lamivudine was initially used for treating HIV infection in AIDS patients and now is used frequently for treating HBV infection.

Dr Yeo, an associate professor in the Department of Clinical Oncology at the Chinese University of Hong Kong, treated 27 HBV-carrying breast cancer patients with lamivudine before, during and up to eight weeks after chemotherapy. She compared the results with a control group of 41 consecutive patients who had had chemotherapy without lamivudine and compared the incidence of HBV reactivation, hepatitis, severe hepatitis and any consequent disruption to the chemotherapeutic regime.

"We found that lamivudine significantly reduced the incidence of HBV reactivation, and that the incidence of hepatitis from all causes was reduced," said Dr Yeo.

Only two patients out of the 27 receiving lamivudine suffered HBV reactivation compared with 17 out of 41 in the control group (seven per cent versus 41 per cent); three patients in the study group suffered from hepatitis and two from severe hepati
'"/>

Contact: Emma Mason
wordmason@aol.com
49-403-569-3625
Federation of European Cancer Societies
18-Mar-2004


Page: 1 2

Related biology news :

1. Atacama rover helps NASA learn to search for life on Mars
2. Reducing allergens in the home helps inner-city children with asthma
3. As informatics grows, Indiana University helps set research agenda
4. New diagnostic technology helps justify earlier cataract surgery
5. New technique helps scientists reveal interactions between genes and drugs
6. Living at home helps young mothers stay in school
7. Hormone helps fish to mate, may affect human hearing
8. Harmless virus helps slow HIV by boosting immune proteins
9. Study helps explain island populations susceptibility to exotic diseases
10. Utah scientist helps discover new mouse species -- and maybe a new genus
11. Choice of food helps hungry caterpillar

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... -- NXT-ID, Inc. (NASDAQ:   NXTD ) ("NXT-ID" ... of independent Directors Mr. Robin D. Richards and ... furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive Officer ... guidance and benefiting from their considerable expertise as we move ...
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC ... announced that the United States Patent and Trademark Office ... broadly covers the linking of an iris image with ... transaction) and represents the company,s 45 th issued ... patent is very timely given the multi-modal biometric capabilities ...
Breaking Biology News(10 mins):
(Date:4/21/2017)... ... April 21, 2017 , ... The ... the focus of researchers, engineers, product developers, and industry suppliers gathered last week ... by SPIE, the international society for optics and photonics , the event ...
(Date:4/20/2017)... , ... April 20, 2017 , ... ... , this new webinar will explore challenging patient cases when screening for direct ... hospital, there may be a need for bridging parental anticoagulation especially for those ...
(Date:4/20/2017)... ... April 20, 2017 , ... Husson ... clinical research community’s growing body of knowledge during its Eighth Annual Research ... and the adjacent Darling Atrium. During the event, undergraduates, graduate students, and faculty ...
(Date:4/20/2017)... ... April 20, 2017 , ... Parallel6™ , the leader ... announced today that they were named one of the 2017 Top 10 eClinical ... developments in the pharmaceutical industry. , “We take pride in honoring Parallel6 as one ...
Breaking Biology Technology:
Cached News: