HOME >> BIOLOGY >> NEWS
AIDS drug helps to keep HBV at bay during chemotherapy for breast cancer

Hamburg, Germany: Researchers in Hong Kong have discovered a way to help prevent the reactivation of the hepatitis B virus in women who are being treated with chemotherapy for breast cancer.

Dr Winnie Yeo told the 4th European Breast Cancer Conference in Hamburg: "In several developing countries, as many as twelve per cent of breast cancer patients carry the hepatitis B virus. These patients are at risk of developing HBV reactivation during chemotherapy, which is a well-known complication resulting in varying degrees of liver damage that may lead to death."*

Chemotherapy suppresses the immune system and therefore allows the virus to replicate. Once chemotherapy stops, the immune system recovers and attempts to clear the virus and this causes the biochemical flare-up of hepatitis.

However, Dr Yeo has found that the anti-viral drug lamivudine can reduce the risk of HBV reactivation during and after chemotherapy. Lamivudine was initially used for treating HIV infection in AIDS patients and now is used frequently for treating HBV infection.

Dr Yeo, an associate professor in the Department of Clinical Oncology at the Chinese University of Hong Kong, treated 27 HBV-carrying breast cancer patients with lamivudine before, during and up to eight weeks after chemotherapy. She compared the results with a control group of 41 consecutive patients who had had chemotherapy without lamivudine and compared the incidence of HBV reactivation, hepatitis, severe hepatitis and any consequent disruption to the chemotherapeutic regime.

"We found that lamivudine significantly reduced the incidence of HBV reactivation, and that the incidence of hepatitis from all causes was reduced," said Dr Yeo.

Only two patients out of the 27 receiving lamivudine suffered HBV reactivation compared with 17 out of 41 in the control group (seven per cent versus 41 per cent); three patients in the study group suffered from hepatitis and two from severe hepati
'"/>

Contact: Emma Mason
wordmason@aol.com
49-403-569-3625
Federation of European Cancer Societies
18-Mar-2004


Page: 1 2

Related biology news :

1. Atacama rover helps NASA learn to search for life on Mars
2. Reducing allergens in the home helps inner-city children with asthma
3. As informatics grows, Indiana University helps set research agenda
4. New diagnostic technology helps justify earlier cataract surgery
5. New technique helps scientists reveal interactions between genes and drugs
6. Living at home helps young mothers stay in school
7. Hormone helps fish to mate, may affect human hearing
8. Harmless virus helps slow HIV by boosting immune proteins
9. Study helps explain island populations susceptibility to exotic diseases
10. Utah scientist helps discover new mouse species -- and maybe a new genus
11. Choice of food helps hungry caterpillar

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/18/2016)... , March 18, 2016 ... Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical infrastructure ... & security companies in the border security market and the ... and Europe has led visiongain ... companies improved success. --> defence & security ...
(Date:3/15/2016)... March 15, 2016 --> ... by Transparency Market Research "Digital Door Lock Systems Market - ... - 2023," the global digital door lock systems market in ... 2014 and is forecast to grow at a CAGR of ... small and medium enterprises (MSMEs) across the world and high ...
(Date:3/14/2016)... NXTD ) ("NXT-ID" or the "Company"), a company ... of a new series of commercials on Time Warner Cable ... .  The commercials will air on Bloomberg TV, Fox Business ... show. --> NXTD ) ("NXT-ID" or the "Company"), ... the airing of a new series of commercials on Time ...
Breaking Biology News(10 mins):
(Date:5/19/2016)... - I dati saranno presentati ... 52 ° Congresso della Società ... - Le conclusioni dello studio indicano un tasso di ... cui il 90% presenta una d urata della risposta ... settantadue per cento dei pazienti ha riscontrato un beneficio clinico. ...
(Date:5/18/2016)... ... May 18, 2016 , ... Shimadzu ... at The University of Toledo. This two-day camp will take place annually starting ... the field of pharmaceutical sciences in preparation for a university academic program. ...
(Date:5/18/2016)... ... May 18, 2016 , ... STACS DNA Inc., the sample tracking software company, ... sexual assault kit processing to help them save time and reduce errors. , Sexual ... to be processed and victims informed of results. Due to a previous lack of ...
(Date:5/18/2016)... ... May 18, 2016 , ... The Academy of Model Aeronautics has ... dream of reaching a total of $1 million in awarded scholarships. , The AMA ... school graduates from across the nation has helped bring the total of AMA scholarships ...
Breaking Biology Technology:
Cached News: