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AIDS drug helps to keep HBV at bay during chemotherapy for breast cancer

tis (eleven and seven per cent) compared with 27 patients in the control group who developed hepatitis and six who developed severe hepatitis (66 and 15 per cent). Chemotherapy was disrupted in seven (26 per cent) of the study group and in 21 (51 per cent) of the control group.

Patients in both groups were similar, although more patients were being treated with anthracyclines in the lamivudine group (26 out of 27 patients) than in the control group (23 out of 41 patients).

Dr Yeo said: "These results show very clearly that prophylactic lamivudine significantly reduces the incidence of both HBV reactivation and hepatitis. Therefore I propose that breast cancer patients who are hepatitis B carriers should have anti-viral treatment before the start of chemotherapy."


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Contact: Emma Mason
wordmason@aol.com
49-403-569-3625
Federation of European Cancer Societies
18-Mar-2004


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