Conclusion: The researchers found that participation in a resistance exercise program resulted in a significant improvement in muscle strength, power, and lean body mass compared to a standard rehabilitation program without exercise.
Source: Journal of Applied Physiology, September 2001
A BABY STEP FORWARD IN UNDERSTANDING NEWBORN LIVER DISEASE
Cloning of A 200 Million-Year Old Evolutionary Relative May Shed Light on Liver Disease in Newborns
Summary: Bile secretion is a fundamental function of the liver of all vertebrates. The Bile Salt Export Pump (BSEP) is the major thoroughfare for excreting bile salts from the body and is responsible for production of bile flow. Mutations in the human BSEP result in a form of liver disease called progressive intrahepatic cholestasis, or PFIC Type II. PFIC Type II is characterized by persistent neonatal impaired bile flow, aspects of neonatal hepatitis, and subsequent cirrhosis of the liver caused by obstruction or infection. This study presents evidence that the BSEP evolved early in vertebrate evolution and that its functional properties have remained essentially unchanged despite 200 million years of evolution.
Methodology: To determine the evolutionary origin and structure-function relationship of the human BSEP, a full-length clone of a marine skate (R
Contact: Donna Krupa
American Physiological Society