HOME >> BIOLOGY >> NEWS
Actonel significantly reduced moderate and severe vertebral fractures

San Antonio, TX (September 20, 2002) A new analysis of scientific data presented at today's meeting of the American Society for Bone and Mineral Research (ASBMR) showed that a 5 mg dose of Actonel (risedronate sodium tablets) daily significantly reduced moderate and severe vertebral fracture risk by 70 percent within one year in postmenopausal women with osteoporosis. Furthermore, the significant effect on vertebral fracture risk was sustained over three years.

This analysis combined data from two large Actonel clinical trials, VERT-NA and VERT-MN, which included postmenopausal women with either one prevalent vertebral fracture and low bone mineral density (BMD), or with at least two prevalent vertebral fractures. The objective of this analysis was to compare the incidence of moderate or severe vertebral fracture at one year in women who received Actonel or placebo. Fracture severity was determined using the fracture severity scoring system developed by Harry Genant, M.D., Professor of Radiology, Medicine, Epidemiology and Orthopaedic Surgery at the University of California, San Francisco, an investigator and pioneer of the assessment method used in the analysis.

Recent studies show severity of prevalent vertebral fractures is a predictor of future vertebral and non-vertebral fracture risk; patients with more severe baseline vertebral fractures are more likely to experience subsequent vertebral and non-vertebral fractures. Therefore, reducing the incidence of moderate or severe vertebral fractures may help decrease the risk of future fractures.

"The ultimate goal of osteoporosis treatment is to prevent fractures," said Dr. Genant, "These new findings, combined with previous Actonel clinical data showing reductions in both risk of first vertebral fracture and multiple vertebral fractures, suggest that Actonel reduces fracture risk across a range of osteoporotic severity."

According to
'"/>


20-Sep-2002


Page: 1 2 3 4

Related biology news :

1. Rare mutations can significantly increase risk factor for heart disease
2. Cancer health risk significantly underestimated by EPAs ambient model estimates
3. Double mastectomies significantly lower risk of breast cancer in women who are genetically at risk
4. HAART therapy significantly prolongs survival in AIDS patients with central nervous system lymphoma
5. ENBREL rapidly, significantly improved back pain, mobility, function in ankylosing spondylitis
6. Once weekly ENBREL significantly reduced rheumatoid arthritis pain, inflammation & improved function
7. Cognitive abilities increase significantly with time in most prematurely born children
8. Combining key ingredients of vegetarian diet cuts cholesterol significantly, says study
9. Pollen productionand allergiesmay rise significantly over next 50 years
10. Brain size in premature infants significantly smaller than full-term babies
11. Multicenter study shows Benecol spread significantly reduces cholesterol levels in patients taking statin drugs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/20/2018)... ... November 20, 2018 , ... The Utah Department of Health (UDOH) has ... screening (NBS) specimens across the state. The system will be deployed to all ... state newborn screening laboratory in Salt Lake City. This supports UDOH’s goals of saving ...
(Date:11/15/2018)... ... 2018 , ... Superior Controls, Inc. , a leading ... employees on both the east and west coasts, today announced the company has ... control system integrators must pass an intensive audit every three years to demonstrate ...
(Date:11/15/2018)... , ... November 14, 2018 , ... ... testing lab, will present new scientific evidence on gene-disease relationships and how it ... Meeting to be held in Atlanta, November 14-17. , Ambry has been ...
Breaking Biology News(10 mins):
(Date:11/6/2018)... ... November 06, 2018 , ... Crucial Data ... data collection and management. TrialKit ™, an eClinical platform, has incorporated Apple’s ... quickly and easily sign in to the app via facial recognition or fingerprint ...
(Date:11/5/2018)... Tenn. (PRWEB) , ... November 05, 2018 , ... ... radiology and telemedicine company backed by Siemens Healthineers and several healthcare VC firms ... based radiology solution and making a history by purchasing tokens and obtaining its ...
(Date:11/5/2018)... ... November 05, 2018 , ... 2Blades has completed ... Like (TAL) effector code technology for applications in advancing research in epigenetic technology. ... plants. Since its discovery in 2009, the efficacy of TAL effector-based DNA targeting has ...
(Date:11/3/2018)... ... November 01, 2018 , ... Triangle Insights Group, a premier life sciences consulting ... fastest-growing private companies in the United States, appearing on this year’s Inc. 5000 list. ... on percentage revenue growth over the previous three years. , Separately, Triangle Insights ...
Breaking Biology Technology:
Cached News: