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Aged roaches experience perils of stiff joints, find Case researchers

CLEVELAND Humans are not alone in suffering the ravages of aging. Cockroaches endure it, too.

Case Western Reserve University researchers reported in the Journal of Experimental Biology that as the roach's life wanes between 60-65 weeks after the onset of adulthood, and the cockroach slows down, experiences stiff joints and has problems climbing and a decreased spontaneous fleeing response. Death comes shortly after the onset of these movement problems.

Angela Ridgel, a post doctoral fellow at Case, was the lead author on the National Institute of Health-funded study, "Effects of aging on behavior and leg kinematics during locomotion in two species of cockroaches." Her research looked at walking, climbing and righting behavior in the roach species, Blaberus discoidalis. She wrote the paper with Roy Ritzmann, professor of biology, and Paul Schaefer, a former Case graduate student who studied escape behavior in Periplaneta americana and contributed information about the roach's central nervous system and escape behavior.

Research for the paper came from Ritzmann's cockroach laboratory that studies insect movement to help engineer a new generation of robots that can not only move but sense information as they travel rugged terrains or locations unsafe for humans.

Roaches reach adulthood after several molts. After 60 weeks into adulthood, Ridgel observed in lab studies that roach movement was much different from their younger adult counterparts.

Aging is complicated for the six-legged roach. Ridgel found that old roaches develop a "tarsus catch" where the joint between its paw section and leg joint in the front (prothoracic) leg hardens causing the leg to list to almost 45 degrees. As the roach moves forward, the front leg catches on the middle (mesothoracic) leg, which causes the roach to trip and to struggle to regain its tripod-like stance and gait.

Ridgel noted that this catch increased from 35 percent of the 60-week-old adults
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Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
18-Dec-2003


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