HOME >> BIOLOGY >> NEWS
Alcohol and thiamine deficiency together: a dangerous combination?

  • Heavy alcohol use is associated with thiamine (Vitamin B1) deficiency.
  • Alcohol and thiamine deficiency together may have a more damaging impact on the brain.
  • Learning and reference memory appear to be the most sensitive to their synergistic effects.
  • The role of thiamine supplementation is examined.
The damaging effects of alcoholism on the body are fairly obvious; the mechanisms by which that damage occurs are less apparent. Researchers and clinicians know that chronic abuse of alcohol may lead to a deficiency in thiamine (also known as Vitamin B1). This deficiency can wreak particular havoc on the brain, causing a wide spectrum of deficits in cognition, behavior, and motor coordination. What researchers now suspect, as noted in a recent study in Alcoholism: Clinical & Experimental Research, is that chronic alcohol consumption and thiamine deficiency combined may have a synergistic and even more devastating effect on the brain and mental capacities.

"We were looking for an interaction between ethanol and thiamine deficiency," explained Philip J. Langlais, professor of psychology at San Diego State University, professor of neurosciences at the University of California - San Diego, and lead author of the study. "We wanted to see if you took thiamine deficiency and combined it with chronic alcohol intake, would you then create a situation that would produce a more severe impairment of cognition and memory than you would with either thiamine deficiency alone, or exposure to chronic alcohol ingestion alone." Using rat subjects, they did indeed find a synergistic effect, sometimes. Learning (for example, figuring out the rules of chess) and reference memory (remembering and consistently applying the rules) appeared the most sensitive to the damaging, synergistic effects of alcohol and thiamine deficiency. Short-term working memory (incorporating the rules of chess into game strategies), on the other hand,
'"/>

Contact: Philip J. Langlais, Ph.D.
planglai@sunstroke.sdsu.edu
619-594-2208
Alcoholism: Clinical & Experimental Research
21-May-2000


Page: 1 2 3 4

Related biology news :

1. Alcohol-use and depression among pregnant and postpartum women
2. Alcoholism risk linked to gene involved in brain chemistry
3. Alcohol consumption can damage hearing
4. Alcohol-dependence gene identified
5. Alcohol exposure in pre- and early post-natal stages may cause insulin resistance
6. Alcoholics with antisocial personality disorder have blunted emotional reactivity
7. Alcohols pharmacological properties, not smell or taste, reinforce its effects
8. Alcohol abuse may increase susceptibility to HIV infection
9. Alcohol researchers relate a genetic factor to anxiety in women
10. Alcohol researchers identify a genetic basis of pain response
11. Alcohols effects on testosterone

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... NEW YORK , March 30, 2017 ... by type (physiological and behavioral), by technology (fingerprint, AFIS, ... recognition, voice recognition, and others), by end use industry ... travel and immigration, financial and banking, and others), and ... Europe , Asia Pacific ...
(Date:3/28/2017)... -- The report "Video Surveillance Market by ... Devices), Software (Video Analytics, VMS), and Service (VSaaS, Installation ... 2022", published by MarketsandMarkets, the market was valued at ... reach USD 75.64 Billion by 2022, at a CAGR ... considered for the study is 2016 and the forecast ...
(Date:3/24/2017)... MILAN , March 24, 2017 The Controller ... Deputy Controller Mr. Abdulla Algeen have received the prestigious international ... Continue Reading ... ... small picture) and Deputy Controller Abdulla Algeen (small picture on the right) ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... , ... AMRI, a global contract research, development and manufacturing ... and quality of life, will now be offering its impurity solutions as a ... requirements for all new drug products, including the finalization of ICH M7 earlier ...
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its ... 2018 in San Francisco, CA. The Summit brings together current and former FDA office ... directors and government officials from around the world to address key issues in device ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study ... in frozen and fresh in vitro fertilization (IVF) transfer cycles. The ... IVF success. , After comparing the results from the fresh and frozen transfer ...
(Date:10/10/2017)... ... 2017 , ... Dr. Bob Harman, founder and CEO of VetStem Biopharma, ... The event entitled “Stem Cells and Their Regenerative Powers,” was held on ... DVM, MPVM was joined by two human doctors: Peter B. Hanson, M.D., Chief of ...
Breaking Biology Technology:
Cached News: