HOME >> BIOLOGY >> NEWS
Alcohol consumption during pregnancy alters thyroid function

tal development are similar to brain abnormalities found in children exposed to alcohol in utero. "From a behavioral standpoint," said Cudd, "children born to hypothyroid mothers score less well on intelligence, attention, language, reading ability and school performance measures compared to children born to mothers with normal thyroid function. These deficiencies are similar to those in children with ARBDs. From an anatomical perspective, hypothyroidism and fetal alcohol exposure both affect the development of the hippocampus and the cerebellum." Knowing these similarities, the study authors investigated if ARBDs are, in part, a result of alcohol-mediated thyroid hormone system dysfunction.

Researchers gave pregnant ewes alcohol doses of 0.75, 1.25, 1.5 or 1.75 g/kg or saline through catheters beginning on day 109 of gestation (a full term for sheep is 145 days). The ewes received alcohol or saline on three consecutive days, followed by four days without exposure, thereby mimicking a pattern of binge drinking. Fetal and maternal blood samples were collected on days 118 or 132.

"The administration of alcohol to sheep during the equivalent of the third trimester of pregnancy resulted in altered thyroid function in both the mother and fetus," said Cudd.

"This is an important study because even today so little is known regarding the mechanisms through which alcohol intake by pregnant mothers is bad for their fetuses," said Catherine Rivier, a professor of neuroendocrinology/neurosciences at The Salk Institute. "In addition, the sheep is a good model for the human because the thyroid system of both species develops similarly during gestation. Prior to this study, we knew that, in general, fetal brain development requires thyroid hormones to grow normally and build all the right connections. We knew that children born to mothers who have low thyroid hormone levels are often retarded. These results show us that alcohol given to a
'"/>


15-Jan-2002


Page: 1 2 3

Related biology news :

1. Alcohol-use and depression among pregnant and postpartum women
2. Alcoholism risk linked to gene involved in brain chemistry
3. Alcohol consumption can damage hearing
4. Alcohol-dependence gene identified
5. Alcohol exposure in pre- and early post-natal stages may cause insulin resistance
6. Alcoholics with antisocial personality disorder have blunted emotional reactivity
7. Alcohols pharmacological properties, not smell or taste, reinforce its effects
8. Alcohol abuse may increase susceptibility to HIV infection
9. Alcohol researchers relate a genetic factor to anxiety in women
10. Alcohol researchers identify a genetic basis of pain response
11. Alcohols effects on testosterone

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/20/2016)... MINNEAPOLIS , May 20, 2016  VoiceIt ... technology partnership with VoicePass. By working ... user experience.  Because VoiceIt and VoicePass take slightly ... two engines increases both security and usability. ... expressed excitement about this new partnership. ...
(Date:5/12/2016)... WearablesResearch.com , a brand of Troubadour ... from the Q1 wave of its quarterly wearables survey. ... receptivity to a program where they would receive discounts ... company. "We were surprised to see that ... LaColla , CEO of Troubadour Research, "primarily because there ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
(Date:6/23/2016)... 23, 2016  The Biodesign Challenge (BDC), a university ... to harness living systems and biotechnology, announced its winning ... New York City . ... showcased projects at MoMA,s Celeste Bartos Theater during the ... MoMA,s senior curator of architecture and design, and ...
(Date:6/23/2016)... 23, 2016 Apellis Pharmaceuticals, Inc. today ... trials of its complement C3 inhibitor, APL-2. The ... ascending dose studies designed to assess the safety, ... injection in healthy adult volunteers. Forty ... a single dose (ranging from 45 to 1,440mg) ...
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory Compliance Associates® Inc. (RCA), ... free webinar on Performing Quality Investigations: Getting to Root Cause. ... no charge. , Incomplete investigations are still a major concern to the Regulatory ...
Breaking Biology Technology:
Cached News: