The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Allelix drug increases bone density and content in women with osteoporosis

SAN FRANCISCO, Dec. 3, 1998 -- Allelix Biopharmaceuticals (TSE/ME: AXB) announced today results of a Phase II clinical trial demonstrating that its compound ALX1-11, recombinant human parathyroid hormone significantly increases bone mineral density (BMD) and bone mineral content (BMC) in the spine of women with postmenopausal osteoporosis.

Dr. Robert Lindsay, president of the National Osteoporosis Foundation today reported the results from the double blind, placebo controlled, clinical trial of the drug at the American Society for Bone and Mineral Research (ASBMR) meeting.

"ALX1-11 appears to be a promising novel approach to treat the millions of people with osteoporosis especially that which affects the spine," said Dr. Lindsay, one of the study's principal investigators, who holds the position of professor of clinical medicine at Columbia University School of Medicine. "These data are particularly encouraging because patients at the higher dose had greater increases in bone mass than have been observed with currently available therapies. For the many patients with more advanced osteoporosis, this rapid increase in bone mass and density could be an important clinical benefit."

"These results confirm that ALX1-11 can rapidly increase bone mass and produce new bone," said Dr. John Dietrich, senior vice president of research and development at Allelix. "We believe that ALX1-11 will offer osteoporosis patients an important new option to decrease their risk of experiencing incapacitating fractures."

The Phase II trial was conducted in 18 centers in the United States and Canada and involved 217 women with postmenopausal osteoporosis. The women, who ranged in age from 50-75, gave themselves daily subcutaneous injections of ALX1-11 for one year. The women received one of three doses of the drug or a placebo, for comparison. In addition, to the Allelix drug, all of the women rece
'"/>

Contact: Maria Tenaglia
m.tenaglia@noonanrusso.com
212-696-4455 ext 216
Noonan/Russo Communications
3-Dec-1998


Page: 1 2 3 4

Related biology news :

1. Allelix Clones Receptor For Intestinal Growth Factor GLP-2
2. USC study links historical increases in life span to lower childhood exposure to infection
3. Moderate alcohol consumption increases plasma levels of a protective hormone
4. Protease-inhibitor cocktail protects, increases anti-microbial action of promising new peptide
5. Breast self examination increases womens concerns but has no effect on mortality
6. Educational program increases some safety behaviors for older drivers
7. Placental malaria increases mother-to-child HIV transmission
8. NIEHS-funded researchers find low-level ozone increases respiratory risk of asthmatic children
9. Northwesterns Cancer Genetics Program pinpoints gene that increases cancer risk by 26 percent
10. Common gene variant increases risk of atherosclerosis
11. Prenatal exposure to nicotine increases risk of apnea in brains of newborn rats
Post Your Comments:
(Date:11/27/2008)...s at St. Jude Children,s Research Hospital have id... cells of children with acute lymphoblastic leukem...pathway to designing treatments for ALL relapse in... common childhood cancer, ALL affects thousands of...more than 80 percent of ALL cases are cured, relap...
(Date:11/26/2008)...ife Conservation Society, the Government of Camero... a new national park to help protect the world,s m... , The park now forms part of an important trans...r National Park, safeguarding an estimated 115 gor...along with other rare species. Trans-boundary prot...
(Date:11/26/2008)...pes societies, but it is a factor only just beginn...e Norwegian professor, writer and film maker Terje...gues that water has played a unique and fundamenta...ry. Speaking at a European Science Foundation and ...ed that social scientists and historians have long...
(Date:11/26/2008)...d by University of North Carolina at Chapel Hill r...ne changes in their brains and behavior that may m...ntially expanded after receiving an additional $3....g Study (IBIS), which involves a network of univer... by the National Institutes of Health as an Autism...
Breaking Biology News(10 mins):St. Jude identifies genomic causes of a certain type of leukemia relapse 2St. Jude identifies genomic causes of a certain type of leukemia relapse 3New national park protects world's rarest gorilla 2New national park protects world's rarest gorilla 3Using water to understand human society, from the industrial revolution to global trade 2Using water to understand human society, from the industrial revolution to global trade 3UNC expands brain imaging study of infants at risk for autism 2Active seniors curb health care costs 11920 1Active seniors curb health care costs 11920 2inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 1inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 2inVentiv Health Ranked 2317 by Training Magazine in its 2008 List of Top 125 Training Companies 11918 3The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 1The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 2The Quantum Group Reports 4th Quarter and Year End Results for Fiscal Year 2007 11916 3Newly Released 2009 COLA Forecast Would Keep Five Million Seniors Below Poverty Line 11914 1Newly Released 2009 COLA Forecast Would Keep Five Million Seniors Below Poverty Line 11914 2
Other News:
...olism offer additional insight into how the cells ...le in fueling cells, and oxygen deficiency underli..., stroke, inflammation, and cancer.......The findi...ersy over the identity of mammalian oxygen sensors...
...d and apply scientific methodologies to biology pr... (ISAC) in Temple's College of Engineering has bee...onal Science Foundation to develop three intellige...h-school biology curriculums....Building on the po...
...nce yet that mitochondria -- the organelles that g...xygen concentration in the cell. If oxygen slips b...or" triggers protective responses to promote survi...otects itself against hypoxia (low oxygen) has bot...
...ing ways to eliminate pollution from waterways wit...eating bacteria commonly found in freshwater ponds...dings today at the 105th General Meeting of the Am...are capable of continuously generating electricity...
Studies reveal how cells sense oxygen 2Temple engineers recieve NSF grant to develop interactive high school biology curriculum 2Temple engineers recieve NSF grant to develop interactive high school biology curriculum 3Cell's power plants also sense low oxygen 2Cell's power plants also sense low oxygen 3Pollution-eating bacteria produce electricity 2
...GO NOTE FOR REPORTERS: EACH PAPER LISTED IN THIS T...FIC TIME......ANAHEIM, Calif., March 29 Two years...ly high levels of the chemical acrylamide, a proba...including potato chips, French fries, and some bre...
...gle exposure to cocaine activates different brain ...unpleasant effects of psychoactive drugs, accordin...ct may explain why some people become addicted to ...appears to result from cocaine's effect on two par...
...EN, N.J. -- A Technogenesis Company grown at Stev...icensed to Dow Chemical Company a patent-pending t... V from drinking water. Pioneered by Stevens resea...eng, the innovative technology will be developed b...
...GO (MARCH 30, 2004) Many women report an increase...d with their menstrual cycle, according to finding.... This is the first time this well-known phenomen...t several women reported considerable oral symptom...
health news:Acrylamide in food: Unraveling exposure and risk 2health news:Acrylamide in food: Unraveling exposure and risk 3health news:Single cocaine exposure boosts both drug craving and avoidance 2health news:Single cocaine exposure boosts both drug craving and avoidance 3health news:HydroGlobe licenses new arsenic-removal technology 2
...ould participate in 60 minutes or more of moderate... an expert panel.... ..."The take-home message for...at their children spend at least an hour a day in ...Dr. William B. Strong, a pediatric cardiologist an...
...ould participate in 60 minutes or more of moderate... an expert panel......."The take-home message for ...t their children spend at least an hour a day in s...r. William B. Strong, a pediatric cardiologist and...
...r more aggressive medical care than the physicians...eatment preferences of homeless persons being over...f CHEST, the peer-reviewed journal of the American...s persons are more likely than physicians to want ...
... 14, 2005 Four leading medical, nursing and publi...blic health professionals, today filed a challenge...A) power plant mercury rule. The plaintiffs inclu...can Academy of Pediatrics, the American Nurses Ass...
health news:Children need 60 minutes of daily physical activity, expert panel says 2health news:Children need 60 minutes of daily physical activity, expert panel says 3health news:Children need 60 minutes of daily physical activity, expert panel says 4health news:Children need 60 minutes of daily physical activity, expert panel says 2health news:Children need 60 minutes of daily physical activity, expert panel says 3health news:Children need 60 minutes of daily physical activity, expert panel says 4health news:Homeless prefer aggressive medical treatment 2health news:Homeless prefer aggressive medical treatment 3health news:National medical and public health groups sue EPA 2health news:National medical and public health groups sue EPA 3