Allergies To Rubber Affect 12.5 Percent Of Health Care Workers

One in 10 health care workers frequently exposed to rubber surgical and examination gloves is on the cusp of developing allergy symptoms that could seriously affect both their health and their careers, according to a new study from Johns Hopkins Medical Institutions.

Tests show that 2.5 percent of the group are already having allergic reactions to proteins from the gloves, but another 10 percent are "sensitized" to the proteins: they have special antibodies linked to allergies and specific for the rubber proteins, but no allergy symptoms yet.

"They have produced IgE antibodies, and when these antibodies re-encounter rubber proteins under the right circumstances, they can set off a potentially serious allergic reaction," says Robert G. Hamilton, Ph.D., associate professor of medicine, who led what is believed to be the first definitive U.S. prevalence study of allergies to rubber proteins.

Hamilton presents his group's results, funded by the National Institutes of Health, on March 15 at the annual meeting of the American Academy of Allergy, Asthma and Immunology.

Hamilton has been a leader in efforts to reduce hospital use of products containing rubber, sometimes called latex, for health care professionals and patients. He is concerned that the potentially life-threatening consequences of this allergy are still very underappreciated. Reactions can range from a localized skin rash or sneezing to respiratory distress or death.

"These reactions become progressively worse with repeated exposures, so it's important to identify both those who are sensitized and those who already have allergy symptoms," says Hamilton. "By stopping exposure, we should be able to stop the sensitized but asymptomatic group from developing symptoms."

Examination and surgical gloves are believed to be the main risk factors for health care workers, but other stretcha

Contact: Michael Purdy
Johns Hopkins Medical Institutions

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