HOME >> BIOLOGY >> NEWS
Altadena chemist wins national award for studying life molecules

Chemist John D. Roberts of Altadena, Calif., will be honored April 3 by the world's largest scientific society for his pioneering studies in technology to better understand molecules important to life. He will receive the 2001 Nakanishi Prize from the American Chemical Society at its 221st national meeting in San Diego.

"Over the last quite a few years, my research group and I have found out much about the structures of molecules and how they work - particularly in biochemical processes," said Roberts, who is professor emeritus of chemistry at the California Institute of Technology, Pasadena.

One of his projects has been studying the action of a class of protein enzymes called proteases, the body's scissors. Despite their role in diseases such as AIDS, proteases also snip up food proteins during digestion and perform other processes critical to life.

The research tool Roberts uses is called nuclear magnetic resonance, for whose development colleagues call him a pioneer in the field. NMR is based on the principle that nuclei - those of carbon, nitrogen and so on - will vibrate at some unique frequency when placed in an energy field. Researchers use NMR to identify and analyze compounds.

Specifically, Roberts used NMR in the 1970s to learn more about why proteases are able to cut up other proteins without cutting up themselves. While many proteins fit into the protease active site, where cleavage takes place, the simple answer is that proteases do not.

But his team uncovered important details: "We showed the way in which three protease amino acids [protein subunits] in particular cooperate with each other to attack the bonds," he said, and at the same time disproved a then-popular theory of action.

Roberts continues active research despite retiring officially in 1988. He and his students are now using NMR to study "how and why certain arrangements of molecules are more favorable than others," he said.

The organic chemist received his u
'"/>

Contact: Rodney Pearson
r_pearson@acs.org
202-872-4400
American Chemical Society
3-Apr-2001


Page: 1 2

Related biology news :

1. UT Southwestern biochemist honored with NIH Directors Pioneer Award
2. NJIT chemist speaks Aug. 25 about compound derived from pine tree
3. NIH roadmap for biomedical research focus of chemists at American Chemical Society meeting
4. U of T research answers key question in biochemistry
5. Carnegie Mellon University hosts ACS-PRF summer school on green chemistry
6. Rutgers chemist uses NMR to elucidate protein-DNA interaction
7. New multidisciplinary research tops chemists meeting Aug. 22-26
8. Wisconsin chemists find a new chink in TBs armor
9. UCLA chemists develop new coating for nanoscale probes
10. High profile publications in biology and biochemistry on rise at UH
11. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Altadena chemist wins national award for studying life molecules

(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ("NXT-ID" or ... commerce market releases photos and video of the recent opening bell ... th . Gino Pereira , CEO of ... Mr. Chad A. Verdi rang the bell.  ... and employees "for their work and dedication in bringing the world,s ...
(Date:10/14/2014)... Cancer Research shows SIRT6—a protein known to inhibit ... development of skin cancers by turning on an enzyme ... cells. , Previously considered protective, SIRT6 is part of ... regulate genomic stability and prevent some of the genetic ... which can lead to cancer. This study, in the ...
(Date:10/14/2014)... a new kind of stem cell that can become either ... vessels, according to a study published today in the journal ... cell type contradicts current theory on how organs arise from ... origins of, and future treatment for, liver cancer., Thanks to ... complex being made up of more than 200 cell types. ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
(Date:10/20/2014)... 20, 2014 Asterias Biotherapeutics, Inc. (NYSE ... signed a Notice of Grant Award (NGA) with ... October 1, 2014.  The NGA provides for the ... release of additional grant funds pursuant to the ... clinical development of Asterias, product, AST-OPC1. The grant ...
(Date:10/20/2014)... , Oct. 20, 2014  GenVec, Inc. (NASDAQ: ... Horovitz , Ph.D., from its board of directors effective on ... August 2003, and served as its chairman from June 2006 ... the Nominating and Corporate Governance and Audit Committees of the ... than a decade of dedicated service to GenVec, and its ...
(Date:10/20/2014)... Virginia (PRWEB) October 20, 2014 ... NDA Partners LLC, announced today that Ellen Teplitzky, ... legal support for the pharmaceutical industry, has joined ... manager of its legal services practice. NDA ... and expert witness and testimony, to top law ...
(Date:10/19/2014)... 20, 2014 OCTOBER 20-22, ... (ABIM). ABIM will take place at ... about ABIM 2014 is now available at ... representing companies and organizations from all over ... information on the latest products and developments ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 4Zola P. Horovitz To Retire From GenVec Board 2NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
Cached News: