HOME >> BIOLOGY >> NEWS
Alterations in vitamin D receptor gene increase prostate, breast cancer risk

al Cancer Research.

Intriguingly, the F variant that increases the chance of developing breast cancer when associated with other VDR variants also contributes to increased risk and aggressiveness of prostate cancer in African-American men, according to the Cancer Epidemiology, Biomarkers & Prevention article.

This study reported that men with two copies of the F variant almost doubled the risk for prostate cancer developing in African-Americans, but not Caucasians. Furthermore, the same men had twice the risk for developing high grade advanced prostate cancer, according to the research.

"More African-American prostate cancer patients carried the homozygous FF variant of the vitamin D receptor than African American men who did not have prostate cancer," said Alice S. Whittemore, Ph.D., the senior author of the paper. Whittemore, who conducts cancer research in the department of Health Research and Policy, the Stanford University School of Medicine, led a multi-institutional team of cancer scientists from Stanford University, the University of Southern California, the University of Hawaii, the British Columbia Cancer Agency and the Northern California Cancer Center.

Neither the b nor L gene variants that altered risk in Caucasian women in the British study contributed to elevated risk for prostate cancer among men.

Funding for the prostate cancer studies came from NIH grant CA67044. The UK breast cancer study was funded by Breast Cancer Campaign and the World Cancer Research Fund.


'"/>

Contact: Russell Vanderboom, PhD
vanderboom@aacr.org
215-440-9300
American Association for Cancer Research
6-Aug-2004


Page: 1 2

Related biology news :

1. Genetic Alterations Linked To Cancer In Some Blood Samples
2. Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
3. Chemical derived from vitamin-E shows early promise as cancer drug
4. Folic acid vitamin use by women reaches all-time high, March of Dimes survey finds
5. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
6. New antioxidants are 100 times more effective than vitamin E
7. Study finds huge variability in vitamin E absorption
8. People with undetermined muscle/bone pain tend to be severely vitamin D deficient
9. Daily vitamins could prevent vision loss among thousands
10. Drug that mimics vitamin D hormone may boost effectiveness of prostate cancer treatment
11. Strategies to boost womens multivitamin use fall short

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/1/2019)... ... April 01, 2019 , ... Stay on top of current hot topics through ... Access to all webinars is free, so be sure to register today to save ... http://www.xtalks.com to see our upcoming webinars: , CLINICAL TRIALS , April 2 ...
(Date:3/29/2019)... HAMBURG, Germany and WESTMINSTER, Colo. (PRWEB) , ... ... ... Indivumed and Flagship Biosciences, Inc. are pleased to announce a partnership ... clinical services to support advanced oncology diagnostics. , Under the terms ...
(Date:3/27/2019)... ... ... Evan Holden , a shareholder in the Atlanta office ... National Academy of Sciences (NAS) Roundtable on Biomedical Engineering Materials Applications (BEMA), March 25 ... Pharmaceutical, Medical Device & Health Care Litigation Practice , addressed, “Medical Device Liability—How ...
Breaking Biology News(10 mins):
(Date:4/16/2019)... ... April 16, 2019 , ... On ... project partner, the U.S. Army Center for Environmental Health Research (USACEHR), with an ... In-Licensing/Out-Licensing.” , Blue Sources, a veteran-owned company located at the Frederick Innovative Technology ...
(Date:4/12/2019)... Fla. (PRWEB) , ... April 12, 2019 , ... ... explore recent developments in neurotechnology and will educate about innovative tools and devices ... Check your local listings for more information. , This segment of Advancements will ...
(Date:4/9/2019)... ... April 09, 2019 , ... USDM ... capacity of life sciences organizations to accelerate innovation and maximize productivity, announces that ... the past 12 months. , USDM’s Cloud Assurance is a managed ...
(Date:4/8/2019)... BOSTON (PRWEB) , ... April 08, 2019 , ... ... enterprise-class unified communications and collaboration solutions, announced today the launch of their app ... an unprecedented range of business and contact-orientated applications while using CT Cloud Voice ...
Breaking Biology Technology:
Cached News: