HOME >> BIOLOGY >> NEWS
Alzheimer's disease is not accelerated aging

Certain brain changes that are common in normal aging are not the beginnings of Alzheimer's disease. Recent research by cognitive aging experts suggests that changes related to Alzheimer's disease appear in distinct regions of the brain and reflect unique pathology compared with changes that occur in older adults without dementia.

"We're getting a better understanding of the complex constellation of factors that change [in the brain] with aging," said Howard Hughes Medical Institute researcher Randy L. Buckner of Washington University in St. Louis. "When you start to look across the literature, lots of data points converge suggesting there are certain changes that take place in aging that are not what cause Alzheimer's disease."

Buckner is the author of a review article published in the September 30, 2004, issue of Neuron, that points out recurring distinctions between factors that influence what he calls executive function, which more commonly falters with normal aging, and the decline in long-term memory typical of Alzheimer's. Executive function involves the cognitive processes used to complete complex, goal-oriented tasks. Elderly individuals with no symptoms of dementia may have difficulty attending to one thing when distractions are present, for example, or they may experience difficulties in complex, novel situations.

Buckner says the data suggest that changes in executive function are due to age-associated influences on frontal-striatal circuits of the brain, including an area called the corpus callosum a tract of white matter that connects the two cerebral hemispheres. The accelerated memory loss of Alzheimer's disease is more likely due to changes in the medial temporal lobe memory system, which includes the hippocampus.

For brain changes in non-demented aging, Buckner reviews studies that use structural magnetic resonance imaging (MRI) images
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
29-Sep-2004


Page: 1 2 3

Related biology news :

1. Study explores gene transfer to modify underlying course of Alzheimers disease
2. TANGO: towards faster prognosis of Alzheimers and Parkinsons diseases?
3. DHA-rich diet protects brain from Alzheimers damage, UCLA study shows
4. Decreasing toxins in brains of Alzheimers patients keep cognitive deficits at bay
5. Early clinical treatment can halt progression of Alzheimers disease, UCI researchers find
6. New UCF researchers, college will help fight Alzheimers disease, cancer
7. Herpes tool allows researchers to customize Alzheimers vaccine
8. Altered protein involved in a novel link to Alzheimers disease
9. Alzheimers may leave some forms of memory intact
10. Cancer drug resistance research leads to possible therapeutic target for Alzheimers disease
11. SPECT imaging shows promise for accurate, early diagnosis of Alzheimers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... Research and Markets has announced the addition of the ... Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access ... 15.1% over the next decade to reach approximately $1,580 million by ... and forecasts for all the given segments on global as well ...
(Date:3/23/2017)... DUBLIN , Mar. 23, 2017 Research ... Anti-Theft System Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 8.8% over the next ... This industry report analyzes the market estimates and forecasts for all ...
(Date:3/22/2017)... , March 21, 2017 ... Cloud used by retailers such as 1-800-Flowers and ... platform — Product Recommendations and Replenishment. Using Optimove,s machine ... more personalized product and replenishment recommendations to their ... also on predictions of customer intent drawn from ...
Breaking Biology News(10 mins):
(Date:9/14/2017)... ... 2017 , ... One of the world’s largest World Marrow Donor Day events ... that day, the GenCure Marrow Donor Program will be signing up potential donors for ... San Antonio. , The registration tables will be staffed by employees from all the ...
(Date:9/12/2017)... ... 2017 , ... PhysIQ, a Chicago-based company that provides a ... and clinical trial support, earned DPharm Idol 2017 honors at the 7th annual ... in 2005, PhysIQ leverages artificial intelligence (AI) to empower digital health. The company ...
(Date:9/12/2017)... , ... September 12, 2017 , ... ... extremely pleased to announce that Jeremy Nicholson, Head of the Department of Surgery ... will deliver the 2018 Wallace H. Coulter Lecture. His presentation, “Analytical Science ...
(Date:9/12/2017)... ... September 11, 2017 , ... An August 30th article on Daily ... idea that only aging and overweight patients suffer from enlarged veins (genetics are also ... cosmetic concern. , The Washington State clinic Northwest Vein & Aesthetic Center notes ...
Breaking Biology Technology:
Cached News: