American Cancer Society funds Space Station scientist who studies how good cells turn bad

on the Space Station. Just as you bake some dishes and boil others, you process crystals in different ways to get the best results."

In ground-based laboratories, like Borgstahl's at the University of Toledo, researchers mix up and try out thousands of recipes at a time - trying to coax proteins to form crystals that will reveal how they are made.

So why use an orbiting laboratory hundreds of miles away in space?

Some proteins form crystals perfectly on the ground. Some form small, irregular crystals that are difficult to study and won't reveal how proteins are made. Some won't form crystals at all.

In the microgravity environment created as the Space Station orbits Earth, crystals float in their solutions - much like the astronauts float through the Station. On Earth, the heavy crystals sediment, or sink, to the bottom of flasks and often stick together. This sometimes results in small, cracked, poorly formed crystals.

Borgstahl and Snell got their first taste of success on the STS-95 Space Shuttle mission in October 1998 when U.S. Sen. John Glenn of Ohio helped grow crystals of insulin in microgravity for the Hauptman-Woodward Medical Research Institute in Buffalo, New York. Snell and Borgstahl analyzed the quality of the insulin crystals. They found the space-grown crystals were 34 times larger than those grown on the ground. (Acta Crystallographic, 2001, D57, 254-259)

"More importantly than being large, the crystals had better internal order," said Snell. "Our thorough analysis showed microgravity passed the test, providing the best environment for growing macromolecules of these proteins."

Better internal order means that scientists can fire X-ray beams at the crystal and learn how it is made at the atomic an/or electronic level. It is like working a puzzle backwards. You have a crystal - the completed puzzle -- but you need to learn how the pieces - in this case the molecules - fit together to form th

Contact: Steve Roy
NASA/Marshall Space Flight Center News Center

Page: 1 2 3 4

Related biology news :

1. Highlights of the October 2004 Journal of the American Dietetic Association
2. The American Phytopathological Society announces 2004 awards
3. Tips from the Journals of the American Society for Microbiology
4. Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
5. NIH roadmap for biomedical research focus of chemists at American Chemical Society meeting
6. Tips from the journals of the American Society for Microbiology
7. Genetic mutation linked to more aggressive breast cancer found more often in African-Americans
8. More aggressive breast cancer tumors found in African American women
9. American Society of Mammalogists honors CI president Russell Mittermeier with Aldo Leopold award
10. Tips from the Journals of the American Society for Microbiology
11. Most Americans not sure about the sources of high cholesterol

Post Your Comments:

(Date:10/29/2015)... BOSTON , Oct. 29, 2015  Connected health ... phenomena driving the explosion of technology-enabled health and wellness, ... his new book, The Internet of Healthy ... apps, sensors or smartphones even existed, Dr. Kvedar, vice ... model of health care delivery, moving care from the ...
(Date:10/27/2015)... 2015 In the present market scenario, security ... various industry verticals such as banking, healthcare, defense, electronic ... demand for secure & simplified access control and growing ... hacking of bank accounts, misuse of users, , and ... PC,s, laptops, and smartphones are expected to provide potential ...
(Date:10/26/2015)... 26, 2015 ... ReportnsReports.com adds Biometrics Market Shares, Strategies ... well as Emerging Biometrics Technologies: Global ... its collection of IT and Telecommunications ... --> http://www.reportsnreports.com/reports/427352-biometrics-market-shares-market-strategies-and-market-forecasts-2015-to-2021.html . ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... ... 2015 , ... A long-standing partnership between the Academy of ... formalized with the signing of a Memorandum of Understanding. , AMA Executive Director ... Minter and Capt. Albert Glenn Tuesday, November 24, 2015, at AMA Headquarters in ...
(Date:11/24/2015)... , Nov. 24, 2015  Asia-Pacific (APAC) holds ... organisation (CRO) market. The trend of outsourcing to ... margins but higher volume share for the region ... scale, however, margins in the CRO industry will ... Market ( http://www.frost.com/sublib/display-report.do?id=P86A-01-00-00-00&src=PR ), finds that the ...
(Date:11/24/2015)... , Nov. 24, 2015 /CNW/ - iCo Therapeutics ... today reported financial results for the quarter ended ... expressed in Canadian dollars and presented under International ... United States ," said Andrew Rae ... advancements regarding iCo-008 are not only value enriching ...
(Date:11/24/2015)... Global, Inc., a worldwide provider of clinical research services headquartered in ... company has set a new quarterly earnings record in Q3 of ... for Q3 of 2014 to Q3 of 2015.   ... with the establishment of an Asia-Pacific office ... Kingdom and Mexico , with the ...
Breaking Biology Technology:
Cached News: