HOME >> BIOLOGY >> NEWS
American Cancer Society funds Space Station scientist who studies how good cells turn bad

on the Space Station. Just as you bake some dishes and boil others, you process crystals in different ways to get the best results."

In ground-based laboratories, like Borgstahl's at the University of Toledo, researchers mix up and try out thousands of recipes at a time - trying to coax proteins to form crystals that will reveal how they are made.

So why use an orbiting laboratory hundreds of miles away in space?

Some proteins form crystals perfectly on the ground. Some form small, irregular crystals that are difficult to study and won't reveal how proteins are made. Some won't form crystals at all.

In the microgravity environment created as the Space Station orbits Earth, crystals float in their solutions - much like the astronauts float through the Station. On Earth, the heavy crystals sediment, or sink, to the bottom of flasks and often stick together. This sometimes results in small, cracked, poorly formed crystals.

Borgstahl and Snell got their first taste of success on the STS-95 Space Shuttle mission in October 1998 when U.S. Sen. John Glenn of Ohio helped grow crystals of insulin in microgravity for the Hauptman-Woodward Medical Research Institute in Buffalo, New York. Snell and Borgstahl analyzed the quality of the insulin crystals. They found the space-grown crystals were 34 times larger than those grown on the ground. (Acta Crystallographic, 2001, D57, 254-259)

"More importantly than being large, the crystals had better internal order," said Snell. "Our thorough analysis showed microgravity passed the test, providing the best environment for growing macromolecules of these proteins."

Better internal order means that scientists can fire X-ray beams at the crystal and learn how it is made at the atomic an/or electronic level. It is like working a puzzle backwards. You have a crystal - the completed puzzle -- but you need to learn how the pieces - in this case the molecules - fit together to form th
'"/>

Contact: Steve Roy
steve.roy@msfc.nasa.gov
256-544-0034
NASA/Marshall Space Flight Center News Center
2-May-2002


Page: 1 2 3 4

Related biology news :

1. Highlights of the October 2004 Journal of the American Dietetic Association
2. The American Phytopathological Society announces 2004 awards
3. Tips from the Journals of the American Society for Microbiology
4. Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
5. NIH roadmap for biomedical research focus of chemists at American Chemical Society meeting
6. Tips from the journals of the American Society for Microbiology
7. Genetic mutation linked to more aggressive breast cancer found more often in African-Americans
8. More aggressive breast cancer tumors found in African American women
9. American Society of Mammalogists honors CI president Russell Mittermeier with Aldo Leopold award
10. Tips from the Journals of the American Society for Microbiology
11. Most Americans not sure about the sources of high cholesterol

Post Your Comments:
(Date:2/25/2015)... ROCK, Ark. , Feb. 25, 2015 /PRNewswire/ ... software and billing in the Health and Fitness ... as well as to MYiCLUBonline.  The latest upgrade ... and the inclusion of cardless check-in via Identity ... for the first time through interactive displays at ...
(Date:2/23/2015)... Conn. , Feb. 23, 2015 NXT-ID, ... or the "Company"), a biometric authentication company focused on ... has filed provisional patent 62114357 for DISTRIBUTED ... this patent, NXT-ID introduces a new groundbreaking payment method. ... the payment account may only be accessed if both ...
(Date:2/12/2015)... Minn. , Feb. 12, 2015   ... company specializing in clinical study management systems, has ... Program , further distinguishing iMedNet ... Clinical Research Organizations (CROs) and healthcare consultants.  Building ... support, prospective customer referrals and numerous co-marketing opportunities), ...
Breaking Biology News(10 mins):ABC Financial Unveils New Software Enhancements 2ABC Financial Unveils New Software Enhancements 3NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2
(Date:3/6/2015)... Die SARAH-Studie ... Assistance Publique - Hôpitaux de ... französische, gemeinschaftliche, randomisierte Kontrollstudie für die mehr ... werden Patienten mit fortgeschrittenem hepatozellulärem Karzinom (HCC), ... behandelt wurden. Die Ergebnisse werden für Ende ...
(Date:3/5/2015)... , March 5, 2015   HX360 ... semi-finalists in the HX360 Innovation Challenge competition. ... will compete to be chosen as one of four ... of senior health system executives and venture capitalists during ... Innovation Challenge takes place at the 2015 HIMSS Annual ...
(Date:3/5/2015)... Altamonte Springs, FL (PRWEB) March 05, 2015 ... Jamie Damm for the position of Vice President of ... support managed care relationships for one of the nation’s ... Seattle, brings more than 15 years of specialty pharmacy ... Previously Damm worked with Raptor Pharmaceuticals, Vertex Pharmaceuticals, and ...
(Date:3/5/2015)... TORONTO , March 5, 2015 /PRNewswire/ - Aptose ... developing new therapeutics and molecular diagnostics that target the ... G. Rice , Ph.D., Chairman, President and Chief Executive ... Conference on Tuesday, March 10 th at 9:30 ... Laguna Niguel, CA. Dr. Rice will provide ...
Breaking Biology Technology:Behandlung von primärem Leberkrebs: SARAH-Studie schließt Rekrutierung ab, Ergebnisse werden für Ende 2016 erwartet 2Behandlung von primärem Leberkrebs: SARAH-Studie schließt Rekrutierung ab, Ergebnisse werden für Ende 2016 erwartet 3Behandlung von primärem Leberkrebs: SARAH-Studie schließt Rekrutierung ab, Ergebnisse werden für Ende 2016 erwartet 4Behandlung von primärem Leberkrebs: SARAH-Studie schließt Rekrutierung ab, Ergebnisse werden für Ende 2016 erwartet 5Behandlung von primärem Leberkrebs: SARAH-Studie schließt Rekrutierung ab, Ergebnisse werden für Ende 2016 erwartet 6HX360 Announces Sixteen Innovation Challenge Semi-finalists Competing To Deliver Solutions That Improve The Patient Experience 2HX360 Announces Sixteen Innovation Challenge Semi-finalists Competing To Deliver Solutions That Improve The Patient Experience 3HX360 Announces Sixteen Innovation Challenge Semi-finalists Competing To Deliver Solutions That Improve The Patient Experience 4BioPlus Specialty Pharmacy Announces Hiring of New Vice President of Managed Care: Jamie Damm 2Aptose Biosciences to Present at the 27th Annual ROTH Conference 2Aptose Biosciences to Present at the 27th Annual ROTH Conference 3
Cached News: