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American Cancer Society funds Space Station scientist who studies how good cells turn bad

e crystal and make each unique protein.

So you shoot X-rays at the crystal. This produces a diffraction pattern that can be reconstructed to create a three-dimensional computer model of the protein's macromolecular structure. Scientists use the model to understand exactly how proteins work in the body or don't work - including how medicines interact with proteins.

Snell, Borgstahl and her team at the University of Toledo will soon be busy analyzing a new batch of 35 experiments fresh from the Space Station. These crystals are of Manganese Superoxide Dismutase, or MnSOD, an enzyme that is an anti-oxidant and plays a role in diseases associated with aging such as diabetes, cancer and neurodegenerative disorders.

Analysis in her Ohio laboratory and flying samples on future Space Station expeditions will bring Borgstahl closer to learning how good cells turn bad.


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Contact: Steve Roy
steve.roy@msfc.nasa.gov
256-544-0034
NASA/Marshall Space Flight Center News Center
2-May-2002


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