o nitric oxide, can narrow the vessel, thus raising the blood pressure. High blood pressure, which affects 50 million Americans, is a major risk factor for heart disease and stroke. In the June, in Circulation: Journal of the American Heart Association, researchers at the National Heart, Lung, and Blood Institute published a study that found that the blood vessels of African Americans were less likely to respond to nitric oxide, providing a possible reason for why they are more susceptible to high blood pressure. "The role of nitric oxide and its derivatives in the future of therapy to lower high blood pressure and the recent development of the nitric oxide-like drug sildenafil, or Viagra, are examples of the hopeful future of nitric oxide research in cardiovascular therapy," says Fuster.

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Contact: Cathy Yarbrough
cathyy@heart.org
214-706-1340
American Heart Association
30-Dec-1998

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