HOME >> BIOLOGY >> NEWS
Animal study finds embryonic stem cells can repair heart muscle

Transplantation of embryonic stem cells can help repair injured heart muscle and improve cardiac function following heart attacks and the development of congestive heart failure (CHF), according to the results of an animal study conducted at Beth Israel Deaconess Medical Center.

The findings raise the possibility of a future treatment option for CHF, which diminishes the heart's pumping ability, leaving patients fatigued, often to the point of debilitation. Nearly 5 million people in the U.S. suffer from CHF. "Congestive heart failure is the last major area of cardiac medicine that remains without a readily available effective treatment," explains BIDMC cardiologist James Morgan, M.D., Ph.D., Herman Dana Distinguished Professor of Medicine at Harvard Medical School and co-author of the study, which appears in the January issue of the Journal of Applied Physiology. "The statistics on this condition are troubling even with optimal medical treatment, a persons chances of surviving for five years with heart failure is only around 50 percent."

Heart failure develops when the heart stops pumping effectively due to the destruction of muscle cells, known as cardiomyocytes. Damage inflicted during a heart attack or myocardial infarction causes massive loss of cardiomyocytes, resulting in ventricular dysfunction. Although heart transplantation has proven very successful in the treatment of CHF, notes Morgan, only a small fraction of organs about 2,000 are actually available for transplant.

Heart disease has been a focus of stem cell research for a number of years, with promising results shown in mice which were treated with adult stem cells. However, previous research utilized fully differentiated muscle cells and had not tested embryonic stem cells in heart muscle that had already been damaged. Morgan, together with the study's lead author Yong Fu Xiao, M.D., Ph.D., of the Department of Cardiology at BIDMC and colleagues, designed this study to determ
'"/>

Contact: Jerry Berger
jberger@caregroup.harvard.edu
617-632-8062
Beth Israel Deaconess Medical Center
27-Dec-2001


Page: 1 2 3

Related biology news :

1. Animal research suggests plant estrogens in soy do not increase breast cancer risk
2. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
3. Animal studies show promise treating severe chronic pain
4. UF researcher: Animals think in their own way, but unlike humans
5. Animal studies show CA4P suppresses development and induces regression of ocular neovascularization
6. Animal study demonstrates carbon monoxide may help heart patients
7. Animals can be induced to cooperate if partners reciprocate and benefits accumulate
8. Animal welfare can now be objectively measured
9. Animals regulate their numbers by own population density
10. UF researchers score gene therapy advance: Animal study shows high blood pressure prevented in future generations
11. Experimental Staph Vaccine Broadly Protective In Animal Studies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2018)... Texas (PRWEB) , ... December 04, 2018 , ... ... supplier, has announced the much-anticipated launch of their 100-liter (26 gallon) SAFEthread Drum. ... SAFEthread Drum in 2017, which brought a much-needed modern redesign to the ...
(Date:11/29/2018)... Calif. (PRWEB) , ... November 29, 2018 , ... ... Technologies, is excited to collaborate with the new NSF Engineering Research Center for ... and clinical collaborators brought together to develop transformative tools and technologies for the ...
(Date:11/27/2018)... (PRWEB) , ... November 26, 2018 , ... ... Dr. Brandon Wuerth, MD, Founder of the website IBDwatch and Gastroenterology Fellow at ... leading scientists and doctors from around the world, Dr. Wuerth will bring to ...
Breaking Biology News(10 mins):
(Date:11/13/2018)... ... November 12, 2018 , ... Dr. Dan ... and Sandy Springs, now welcomes new patients for MTM® Clear Aligners. Offering a ... to traditional braces in the Sandy Springs and Alpharetta areas. Constantly on the ...
(Date:11/9/2018)... ... 2018 , ... uBiome, the leader in microbial genomics, announces ... of Andes Biotechnologies, to its Scientific Advisory Board. Joining the board of leading ... on the genetic studies of hepatitis viruses. The appointment will help uBiome continue ...
(Date:11/6/2018)... ... November 06, 2018 , ... Crucial ... trial data collection and management. TrialKit ™, an eClinical platform, has incorporated ... can quickly and easily sign in to the app via facial recognition or ...
(Date:11/3/2018)... Va. (PRWEB) , ... November 01, 2018 , ... ... first-ever Metrics Champion Consortium Summit. Dr. Jean Mulinde, Senior Advisor, Division of Clinical ... manage risk, monitor safety and ensure data reliability. , What should clinical research ...
Breaking Biology Technology:
Cached News: