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Applied Biosystems introduces new chemistries to increase DNA sequencing productivity

FOSTER CITY, CA September 18, 2002 Applied Biosystems Group (NYSE:ABI), an Applera Corporation business, today announced the launch of two new versions of its BigDye Terminator Cycle Sequencing Kit, designed to increase productivity and improve data quality for DNA sequencing applications. These enhanced products are a result of Applied Biosystems' goal to improve sequencing technologies for rapid, accurate and cost effective DNA analysis for studying human and other genomes.

BigDye Terminator v3.1 Cycle Sequencing Kit is designed for the majority of applications, including de novo sequencing and resequencing. The BigDye Terminator v1.1 Cycle Sequencing Kit is designed for specialty applications, such as sequencing PCR products associated with comparative sequencing when using a rapid instrument run. Together BigDye Terminator v3.1 and v1.1 kits are expected to meet the requirements of nearly all sequencing applications performed today. These new formulations are designed to provide researchers with improved performance in sequencing difficult templates, resulting in longer read lengths and higher success rates.

A large percentage of the finishing costs for production-scale sequencing projects are associated with sequencing difficult templates. Some initial customer test sites have reported obtaining an additional 50-100 high-quality bases when using the new chemistries. With a greater ability to sequence difficult templates, customers are expected to be able to complete projects in less time and to lower the overall cost of sequencing projects. Each kit is compatible with Applied Biosystems genetic analysis instruments.

"With the tandem release of these two products, Applied Biosystems should be able to meet the needs of our entire customer base, which is engaged in all types of DNA sequencing applications," said Michael W. Hunkapiller, Ph.D., President of Applied Biosystems. "These products enable longer sequencing reads and higher suc
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Contact: Lori Murray, Applied Biosystems
murrayla@appliedbiosystems.com
650-638-6130
Porter Novelli
24-Sep-2002


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