FOSTER CITY, CA May 29, 2002 Applied Biosystems (NYSE:ABI), an Applera Corporation business, together with its partner MDS SCIEX, today introduced a high performance mass spectrometer for use in both proteomics and early stage small molecule drug development. The Q TRAP LC/MS/MS System combines two important mass spectrometry technologies for the first time triple quadrupole and ion trap - to identify proteins and peptides in proteomics research and small molecule drug metabolites important in therapeutic development. The system will be on exhibit June 2 at the 50th Annual American Society of Mass Spectrometry Conference in Orlando, FL.

The Q TRAP system provides discovery researchers with a new highly sensitive tool with significant versatility. This system is expected to increase productivity in drug discovery through improved metabolite identification while providing a cost-effective and high performance protein identification platform, said Michael W. Hunkapiller, Ph.D., President of Applied Biosystems. This unique combination of triple quadrupole and ion trap capabilities has the ability to identify more metabolites and more proteins in complex samples than current technologies.

Q TRAP System Combines Benefits of Triple Quadrupole Technology and Ion Trap
The Q TRAP system, based on a patented linear hybrid technology, combines triple quadrupole and ion trap mass spectrometry. Using the Q TRAP system, academic and pharmaceutical researchers performing proteomics work, where multiple peptides and proteins are analyzed, should be able to identify more of these per sample with higher confidence and accuracy than with currently available ion trap systems. Later stage drug discovery researchers analyzing small molecule drug metabolism and ADME - absorption, distribution, metabolism and excretion - are expected to be able to both rapidly identify and quantitate a broad range of metabolites on the same system.

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Contact: Lori Murray, Applied Biosystems
murrayla@appliedbiosystems.com
650-638-6130
Porter Novelli
29-May-2002

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