Applied Biosystems launches Assays-on-Demand SNP genotyping and gene expression products

FOSTER CITY, CA - July 10, 2002 - Applied Biosystems Group (NYSE:ABI), an Applera Corporation business, today announced the launch of its biologically informative Assays-on-Demand products, the most comprehensive product line yet introduced based on information derived from the human genome. This is the first commercial product line to emerge from genomic data from both the public and private sector human genome sequencing projects. The Assays-on-Demand products leverage data from Celera Genomics Group (NYSE:CRA), Applied Biosystems' sister business group, The SNP Consortium (TSC), the National Center for Biotechnology Information (NCBI), and the Japanese SNP database (JSNP).

The Assays-on-Demand products represent the broadest collection of functionally validated, ready-to-use assays based on the human genome and are the first commercial products resulting from the Applera Genomics Initiative announced in July 2001. The initial set consists of 77,000 assays for SNP genotyping and 4400 assays for quantitative gene expression analysis and is designed using Applied Biosystems' bioinformatics pipeline and proprietary software algorithms. For every assay produced, the target sequence is subjected to an extensive selection and quality control process to screen for those assays that are specific to the gene or SNP of interest for improved specificity and optimal assay design. Additional assays for both gene expression and SNP genotyping are expected to be released on an ongoing basis over the coming months through the Applied Biosystems Knowledge Business. Ultimately, Applied Biosystems plans to offer a genome-wide selection of off-the-shelf SNP assays and a gene expression assay for nearly every human gene and major splice variant.

"By combining information discovered in the sequencing of the human genome with our subsequent resequencing work through the Applera Genomics Initiative, the Applied Biosystems Knowledge Business is providing information-rich p

Contact: Lori Murray, Applied Biosystems
Porter Novelli

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