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Applied Biosystems launches Assays-on-Demand SNP genotyping and gene expression products

xpression products are expected to include an assay for each of the more than 15,000 well-characterized transcripts in the National Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) Project database. Gene expression assays can be selected by gene name, gene symbol, RefSeq or GenBank ID, functional category and other identifiers. Additional gene expression assays are expected to be available later this summer. More information is available at www.appliedbiosystems.com.

SNP Genotyping Assays

Each of the 77,000 SNP genotyping assays includes ready-to-use, functionally validated assays for candidate gene association, candidate region association, linkage mapping and linkage disequilibrium studies. All SNP genotyping assays include information derived from the DNA of 90 individuals from two distinct DNA populations. This information is used to validate the performance of the assay in a laboratory setting and to determine allele frequency, which is important for mapping purposes. SNP products can be selected by NCBI gene or SNP reference ID, gene name/symbol/family, position within a genome location, reference marker, SNP type and allele frequency. These SNP genotyping products provide a high-resolution, gene-centric marker map that should be useful for researchers performing association studies for disease states, potential drug candidates and drug response.

Single nucleotide polymorphisms (SNPs), which occur up to every 100-300 bases in both coding and noncoding regions of the genome, account for the majority of DNA sequence variation in humans. Although SNP research is still evolving, the implications for drug discovery, clinical drug trials, biomedical research and diagnostics offer great promise. Additional assays are expected to become available over the coming months from well-characterized and validated SNPs throughout the human genome. More information is available
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Contact: Lori Murray, Applied Biosystems
murrayla@appliedbiosystems.co
650-638-6130
Porter Novelli
10-Jul-2002


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