HOME >> BIOLOGY >> NEWS
Australian overturns 15 years of nano-science doctrine

An Australian mathematician has thrown 15 years of accepted scientific practice out the window by discovering a design flaw in a key component of the Atomic Force Microscope.

His finding will force a rethink into the design and use of an instrument that has become a cornerstone of scientific measurement and analysis.

Dr John Sader, at University of Melbourne's Department of Mathematics and Statistics, and Particulate Fluids Processing Centre, used established mechanical principles to prove that the popular V-shaped cantilever inadvertently degrades the performance of the instrument, and delivers none of its intended benefits.

Sader's research will be published in the April issue of Review of Scientific Instruments.

In atomic force microscopy, small cantilevers are used to profile surface topography and structure. Shortly after the invention of the Atomic Force Microscope (AFM), almost two decades ago, V-shaped cantilevers were introduced to minimise the effect of lateral forces on image quality, a problem faced by the original rectangular design. Sader's research reveals that this attempt to rectify the lateral force problem was based on a false assumption.

Instead of increasing the resistance to twisting, V-shaped microcantilevers actually maximise twist and degrade the performance of the instrument.

"This finding is surprising and counterintuitive, contradicting accepted practice and manufacturing standards worldwide where the V-shaped cantilever is the standard due to its alleged advantages," says Sader.

Users of the atomic force microscope have long put up with the geometric complexity of the V-shaped microcantilever, with resulting difficulties in calibration and interpretation, to gain improved lateral performance.

Sader's calculations establish that the simple cantilever design of a straight beam proposed for the original atomic force microscope (Physical Review Letters, 1986) offers greatly im
'"/>

Contact: Jason Major
jmajor@unimelb.edu.au
61-383-440-181
University of Melbourne
6-Mar-2003


Page: 1 2

Related biology news :

1. Rare, tiny find in West Australian waters
2. World-first Australian truffle find
3. Australian researchers locate heart attack genes
4. Australian frog is first to make its own chemical weapons
5. New grain variety opens up possibilities for Australian farmers
6. Changes in Australian ecosystems tied to arrival of exotic animals
7. Reefs and atolls of the Australian outback
8. AVAX Technologies receives an additional $3.0 Million (AUD) investment in Australian joint venture from Australian Vaccine Technologies Ltd.
9. Scientists Use Fossilized Emu Eggshells To Discern Changes In Vegetation, Provide Additional Evidence Of Human Impact On Australian Landscape
10. Australian Scientists In World-First Cell Discovery
11. Concerns For Australian Sea Lion

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Australian overturns years nano science doctrine

(Date:6/18/2013)... Medical Research Council, Laboratory of Molecular Biology, has ... ICAAC Young Investigator Award. Torrent is being recognized ... first algorithm to predict antimicrobial regions in proteins. ... are now applying this algorithm to interrogate full ... leads with very appealing results." , Torrent ...
(Date:6/18/2013)... 10% of breast and ovarian cancers are familial in ... attributable to inherited mutations from the parents in genes ... mutations, PARP inhibitors, which are currently in clinical trials, ... option for personalised cancer treatment, an alternative to standard ... of these patients generate resistance to the drug and, ...
(Date:6/17/2013)... with central nervous system infections may well be suffering ... to a study to be published in mBio ... for Microbiology. Researchers have detected the virus in spinal ... nervous system infections of unknown cause, and in an ... and poultry, suggesting animals may serve as reservoirs for ...
Breaking Biology News(10 mins):The American Society for Microbiology honors Marc Torrent 2An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer 2New virus discovered in patients with central nervous system infections 2New virus discovered in patients with central nervous system infections 3
(Date:6/18/2013)... (PRWEB) June 18, 2013 The human skin ... skin as an important human body part. Similar to the ... in order to function, repair and grow. Recent reports from ... and supplements, is just as important as other life supporting ... to aid in skin cell reproduction, increase the appearance of ...
(Date:6/18/2013)... WILMINGTON, Delaware , June 18, 2013 /PRNewswire/ ... to announce the release of the HELM biomolecular ... permissive open source MIT licence. HELM ... of a wide range of biomolecules (e.g. proteins, ... render existing small-molecule and sequence-based informatics methodologies impractical ...
(Date:6/18/2013)... , June 18, 2013 The ... (Sequencing Platforms, Knowledge Management Tools & Data Analysis Services) & ... and studies the Major Market Drivers, Restraints, and Opportunities in ... , Asia-Pacific and Rest of World. ... Tables 22 Figures ...
(Date:6/18/2013)... , June 18, 2013 ... ) has announced the addition of the ... and Companies " to their offering. ... report briefly reviews basics of human genome ... applications. Current large and small sequencers are ...
Breaking Biology Technology:Natural Acne Remedies Through Diet, Probiotic Action Shares New Insight on What Foods May Help Lead to Clear Skin 2The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2Bioinformatics Market Worth $7.5 Billion by 2017 2Bioinformatics Market Worth $7.5 Billion by 2017 3DNA Sequencing: Technologies, Markets and Companies - 2013 Report 2
Cached News: