Avigen's Gene Therapy Approach Shows Promise In Treating Hemophilia B With,,Single Intramuscular Admi...( h allows them to beadministered direct...)

h allows them to be administered directly into patients and to be manufactured, stored and handled like traditional pharmaceutical products. Avigen's scientists have developed a proprietary manufacturing process that improves AAV vector manufacturing and achieves increased yields.

Avigen, Inc., is a biotechnology company involved in the development of gene therapy products derived from adeno-associated virus for the treatment of inherited and acquired diseases. The Company's proposed gene therapy products are designed for in vivo administration to achieve the production of therapeutic proteins within the body. Avigen is focusing its efforts on developing products to deliver genes for the treatment of hemophilia, brain cancer, Parkinson's disease, metabolic storage diseases, and hyperlipidemia.

The Children's Hospital of Philadelphia, the nation's first children's hospital, is a leader in patient care, education, and research. This 304-bed multispecialty hospital provides comprehensive pediatric services to children from birth to age 19.

Except for the historical information contained herein, this news release contains forward-looking statements that involve risks and uncertainties. The Company's actual results may differ materially from those discussed herein. Factors that could cause or contribute to such differences include, but are not limited to, those discussed in this press release, as well as other risks detailed from time to time in documents filed by Avigen with the SEC, including the report on Form 10K/A for the year ended June 30, 1997.

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Contact: Joan Kureczka
JKureczka@aol.com
415-821-2413
Kureczka/Martin Associates
28-May-1998

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