HOME >> BIOLOGY >> NEWS
B-vitamins prove effective in relieving chronic pain

rch Institute, Dallas, TX. They are presenting their findings at the American Physiological Society conference, Experimental Biology 2003, being held April 11-15, 2003, at the San Diego Conference Center, San Diego, CA.

Methodology

Experiments were performed on adult, male Sprague-Dawley rats weighing 200-250 g. CCD was produced by surgically implanting stainless steel rods unilaterally into the intervertebral foramen at L4 and L5 as we previously described. In brief, the rats were anesthetized with sodium pentobarbital (40mg/kg, i.p.), the paraspinal muscles were separated from the mammillary and transverse processes and the intervertebral foramina of L4 and L5 exposed. A stainless steel L-shaped rod, 4 mm in length and 0.6 mm in diameter, was implanted into each foramen, one at L4 and the other at L5. Each insertion was guided by the mammillary process and transverse process.

As the rod was moved over the ganglion, the ipsilateral hind leg muscles typically exhibited one or two slight twitches. After surgery, the muscle and skin layers were sutured. An oral antibiotic, Augmentin, was administered after surgery in the drinking water for each rat (7.52 g in 500 ml) for seven days.

The presence of thermal hyperalgesia was determined by measuring foot withdrawal latency to heat stimulation of surface of hindpaw. The rats were tested on each of 2 successive days prior to surgery. Postoperative tests were conducted 1, 3, 5, 7, 10, 14 days after surgery and then once weekly for ~10 weeks in some rats for examining the long-term effects of B vitamins. For examining short-term effects, tests were conducted for up to 14 days and additional tests 2, 6, 12, 24 and 36 hours after injection of B vitamins on the third day after surgery.

The rats in different groups each received one of the following treatments via i.p. or i.t. I.p. treatments (0.1 ml/100g): (1) saline (0.9% NaCl); (2) B1 (5, 10 and 33 mg/kg, respectively)
'"/>

Contact: Donna Krupa
djkrupa1@aol.com
703-967-2751
American Physiological Society
9-Apr-2003


Page: 1 2 3 4 5

Related biology news :

1. A diet enriched with folate and B-vitamins may provide protection from heart disease
2. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
3. Entrepreneurs to be told how natures secrets can improve business
4. Researchers improve detection of diverse anthrax strains
5. Will a reduction in military spending improve our environmental future?
6. Improved nutrition could reduce malaria burden worldwide
7. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
8. Travelers diarrhea not improved by restricted diet
9. FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
10. K-State researcher working to improve alternatives to equine antibiotics
11. Study shows that ultrasound accreditation improves the quality of ultrasound practice

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: vitamins prove effective relieving chronic pain

(Date:8/22/2014)... the birds and the bees. But that old ... fertilized. The fertilization process for flowering plants is ... male and female reproductive cells. New research from ... Munich, and including Carnegie,s Wolf Frommer, David Ehrhardt, ... signaling process that guides flowering plant fertilization. It ...
(Date:8/21/2014)... -- Nxt-ID, Inc. (OTCQB: NXTD), a biometric authentication company ... that its shares of common stock and the warrants ... proposed underwritten public offering of common stock and warrants ... Market, subject to closing of its proposed underwritten public ... trade under the symbol "NXTD" and "NXTDW," respectively. ...
(Date:8/21/2014)... Aug. 21, 2014 /PRNewswire-iReach/ -- LiveScan Service ... agreed to a partnership with Gabriel Health Institute, ... fastest growing Certified Nursing Assistant preparatory schools. ...  an exclusive member of Binary,s LiveScan service provider,s ... will improve its service capabilities by widening ...
Breaking Biology News(10 mins):Calcium and reproduction go together 2Nxt-ID Approved for NASDAQ Capital Market Listing 2Nxt-ID Approved for NASDAQ Capital Market Listing 3LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3
(Date:8/21/2014)...  BioSpecifics Technologies Corp. (NASDAQ: BSTC ... collagenase-based products marketed as XIAFLEX ® (collagenase ... XIAPEX ® in the EU, today announced ... Phase 2a study of CCH for the potential ... results showed that all three doses of CCH ...
(Date:8/21/2014)... DUBLIN, Ireland , August 21, 2014 ... and Markets ( http://www.researchandmarkets.com/research/3zh3q8/global_hormone ) has announced the ... Market 2014-2018"  report to their offering.  ... also known as hormone therapy, is a ... longer being produced by the body. This ...
(Date:8/21/2014)... NEW YORK , Aug. 21, 2014 Mathematic ... at Harvard University , and funded by the ... aggressive cells within tumors can be visually identified for elimination. ... tumor,s growth. The study, which shows a topological map of ... needed time in cancer research, for while tumor cells can ...
(Date:8/21/2014)... Ontotext S4 , The Self ... . Now the same enterprise hardened text mining, ... unstructured data is available to start-ups and mid-size businesses ... Organizations that do not have resources to evaluate and ... S4 since there is no need for on premise ...
Breaking Biology Technology:BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2Science Power Jeffrey Epstein and Harvard University Fund Project to Visually Stop Tumor Growth 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4
Cached News: