HOME >> BIOLOGY >> NEWS
BIDMC researchers identify source of preeclampsia

BOSTON Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a protein that leads to the development of preeclampsia, a serious and potentially life-threatening complication of pregnancy.

These findings, which could help lead to the development of diagnostic tools and therapies for this baffling condition, appear in the March 2003 issue of The Journal of Clinical Investigation.

Also known as toxemia, preeclampsia occurs in an estimated 5 percent of all pregnancies, affecting approximately 200,000 women in the U.S. each year. The condition typically develops after the 20th week of pregnancy and in mild cases, is characterized by high blood pressure, edema, and protein in the urine. In severe cases, the condition can rapidly develop into eclampsia, in which the mother suffers serious and potentially fatal seizures.

"Currently, there is no treatment for this condition," says the study's lead author S. Ananth Karumanchi, M.D., of the Renal Division at BIDMC and Instructor of Medicine at Harvard Medical School. "The only management we can offer patients is to deliver the baby and the placenta, which can result in the infant being born prematurely." As a result, preeclampsia is one of the leading causes of maternal and infant mortality in developing countries.

In a normal pregnancy, the developing fetus signals the mother's body to widen blood vessels to the placenta, which supplies oxygen and nutrients to the fetus. But, for unknown reasons, in women with preeclampsia the blood vessels grow narrower, impeding the flow of blood and oxygen. The diminished oxygen levels apparently set in motion a rapid progression of potentially fatal complications involving the mother's liver, kidneys, lungs, blood and nervous system.

Scientists have long speculated that the placenta was releasing some unknown factor that was triggering this abnormal course of events. In order to identify this factor, Karumanchi and his colleagues first
'"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
4-Mar-2003


Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... 01, 2020 , ... AltruBio Inc. http://www.altrubio.com , a ... for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European Hematology Association ... of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase 1 single ...
(Date:7/1/2020)... ... 01, 2020 , ... Cure Glioblastoma, a registered 501(c)(3) nonprofit ... aggressive adult brain cancer—announced today the appointments of its first Senior Fellows: John ... the organization’s initiatives and overall vision. , "Senior Fellows are more than advisors; ...
(Date:6/25/2020)... Mass. (PRWEB) , ... June 24, 2020 , ... ... of cloud-based enterprise software and software-driven clinical data services that accelerate drug development, ... for low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... ... 12, 2020 , ... Inc. magazine today revealed that ... compliance consulting has been named on its annual Inc. 5000 list, the most ... look at the most successful companies within the American economy’s most dynamic segment—its ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... collection, today announced Jim Corrigan, President and CEO has been named one of ... broad cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how ...
(Date:7/31/2020)... ... ... R3 Stem Cell International is now offering patients the opportunity to receive four ... may choose which extremities they would like treated. , Several studies have shown just ... R3 International, umbilical cord tissue is obtained from a lab with a long history ...
(Date:7/31/2020)... BEDFORD, Mass. (PRWEB) , ... July 29, 2020 ... ... of highly reliable, solid-state radar transmitter systems that can be configured to drive ... a single controller that can drive one or two switches in a push-pull ...
Breaking Biology Technology:
Cached News: