Bacterial alterations source of persistent COPD lung infections

t kept cropping up were just one strain of bacteria lingering in the body for months or years, or whether different strains of the same bacteria would come and go," said Murphy.

The study successfully recovered about 4000 separate strains of bacteria. New technology involving DNA testing enabled investigators to study the molecular signature of the bacteria, resulting in extremely accurate identification.

"People with COPD may have nothing wrong with their immune systems but they keep getting these recurrent infections our findings may explain why this happens. It appears that when a person gets an infection and makes a good immune response, that response is only good for that particular bacteria strain," said Sethi.

Investigators believe their findings may lead to novel ways to treat bacterial infection. "We can use these observations to understand the immune response to bacteria and possibly develop vaccines that keep pace with the changing strains," said Murphy.

There are 50 patients actively involved in this ongoing study, and enrollment continues. VA's Medical Research Service, will support the project through 2004.


Contact: Arlene Kelly
VA Research Communications Service

Page: 1 2

Related biology news :

1. Bacterial protein recycling factor possible key to new class of antibiotics
2. Bacterial relationships revealed
3. Bacterial viruses make cheap easy vaccines
4. Bacterial infections alter allergic response
5. Bacterial quorum-sensing structure solved
6. Bacterial control of zebra mussels, low power radio
7. Bacterial proteins cause autoimmunity in the antiphospholipid syndrome
8. Bacterial communities found to follow water
9. Bacterial strain may help clean up harmful industrial waste
10. The Largest Bacterium: Scientist Discovers New Bacterial Life Form Off The African Coast
11. Gene Discovery Paves Way For Preventing Deadly Bacterial Shock

Post Your Comments:

(Date:6/9/2016)... Finland , June 9, 2016 ... National Police deploy Teleste,s video security solution to ensure the ... France during the major tournament ... data communications systems and services, announced today that its video ... Prefecture to back up public safety across the ...
(Date:6/3/2016)... LONDON , June 3, 2016 /PRNewswire/ ... Transport Management) von Nepal ... ,Angebot und Lieferung hochsicherer geprägter Kennzeichen, einschließlich ... weltweit führend in der Produktion und Implementierung ... an der Ausschreibung im Januar teilgenommen, aber ...
(Date:6/2/2016)... June 2, 2016   The Weather Company , an ... Ads, an industry-first capability in which consumers will be able ... to ask questions via voice or text and receive relevant ... Marketers have long sought an advertising solution ... can be personal, relevant and valuable; and can scale across ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... published their findings on what they believe could be a new and helpful ... the new research. Click here to read it now. , Biomarkers ...
(Date:6/27/2016)... , June 27, 2016  Liquid Biotech ... the funding of a Sponsored Research Agreement with ... tumor cells (CTCs) from cancer patients.  The funding ... CTC levels correlate with clinical outcomes in cancer ... data will then be employed to support the ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... While ... machines such as the Cary 5000 and the 6000i models are higher end machines ... is the height of the spectrophotometer’s light beam from the bottom of the cuvette ...
(Date:6/23/2016)...   Boston Biomedical , an industry leader ... target cancer stemness pathways, announced that its lead ... Designation from the U.S. Food and Drug Administration ... gastroesophageal junction (GEJ) cancer. Napabucasin is an orally ... stemness pathways by targeting STAT3, and is currently ...
Breaking Biology Technology:
Cached News: