HOME >> BIOLOGY >> NEWS
Bees: Latest Weapon In Cancer Fight

The sting of a bee may soon be used to kill cancer cells.

Scientists at CSIRO Molecular Science are modifying bee venom to develop cancer treatments that should have fewer side effects than other drugs used to fight the disease.

A research project to utilise an active ingredient from bee venom as a potential cure for cancer has been funded by a $670,000 grant from the Commonwealth Government's Industry Research and Development Board. Participants in the project, CSIRO, the Oncology Research Centre at the Prince of Wales Hospital (POWH) and CSL, will contribute further funds towards the $1.3 million project.

The venom in the bee sting contains a number of active ingredients, the main one being mellitin, a molecule that kills cells by slicing through the cell walls, destroying the cells.

"What we have done is to modify the structure of the mellitin molecule to remove the part that causes the allergic reaction while still maintaining its ability to kill cells," CSIRO scientists Dr Werkmeister and Dr Hewish say.

One problem the researchers have to get around is targeting the killing activity of mellitin to cancer cells only and not to normal healthy cells. They plan to achieve this by attaching the modified mellitin to an antibody molecule that specifically recognises cancer cells. This combination of a toxin and an antibody is known as an immunotoxin.

The research team at CSIRO and POWH aims to produce immunotoxins as new cancer drugs that can attack a wide range of cancer cells. This approach should overcome the major drawbacks of chemotherapy treatment.

"Chemotherapy drugs are not specific; they attack normal cells thereby causing unwanted side effects such as hair loss, vomiting and weight loss. Such symptoms limit the amount of drug that can be administered and hence its effectiveness," Dr Hewish says.

The concept of using molecules such as immunotoxins as "magic bullets" for cancer treatment is not new and scientists have crea
'"/>

Contact: Warrick Glynn
warrick.glynn@molsci.csiro.au
61-3-9662-7344
CSIRO Australia
4-Mar-1999


Page: 1 2

Related biology news :

1. Learning From Birds And Bees: Engineers Study Insects For Ideas On Tiny "Micro Air Vehicles"
2. Latest findings on PCBs to be subject of June workshop at Illinois
3. Latest knowledge on plant cell-wall biology in new book
4. Latest research in gene therapy presented at 6th Annual ASGT meeting
5. Latest farm product: Meadowbirds
6. Worlds Leading Echinacea Researchers To Examine Latest Scientific Findings On "Natures Gentle Antibiotic"
7. Renowned Prostate Cancer Experts Present Latest Findings At UCSF Cancer Center Symposium
8. Radioactive Beads Latest Weapon In Fighting Cancer In Dogs, Cats
9. Montana State University Scientist Contributes To Latest Dinosaur Discovery
10. Cystic Fibrosis Conference Will Showcase Latest From Clinical Care To Basic Science
11. Bug Experts Latest Books Feature Simple Language, Vivid Photos

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... -- Today HYPR Corp. , leading innovator in ... the HYPR platform is officially FIDO® Certified . ... that empowers biometric authentication across Fortune 500 enterprises and ... 15 million users across the financial services industry, however ... suites and physical access represent a growing portion of ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... , March 30, 2017  On April 6-7, ... Hack the Genome hackathon at Microsoft,s headquarters ... two-day competition will focus on developing health and wellness ... Hack the Genome is the first ... tremendous. The world,s largest companies in the genomics, tech ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... 11, 2017 , ... Personal eye wash is a basic first aid supply for any work ... which eye do you rinse first if a dangerous substance enters both eyes? It’s one ... with its unique dual eye piece. , “Whether its dirt and debris, or an ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... it will be hosting a Webinar titled, “Pathology is going digital. Is your ... on digital pathology adoption best practices and how Proscia improves lab economics and ...
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , ... of Cancer Research, London (ICR) and ... with SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple ... as MUK nine . The University of ... is partly funded by Myeloma UK, and ICR will perform ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... the implantation and pregnancy rates in frozen and fresh in vitro fertilization ... progesterone and maternal age to IVF success. , After comparing the results from ...
Breaking Biology Technology:
Cached News: