HOME >> BIOLOGY >> NEWS
Benzene responsible for high percentage of leukemia deaths induced by smoking

Benzene, a potent chemical found in cigarette smoke and automobile emissions, appears responsible for between 8 percent and 48 percent of all smoking-induced leukemia deaths, a new University of North Carolina at Chapel Hill study indicates. The chemical also causes between 12 percent and 58 percent of smoking-related deaths from acute myeloid leukemia.

How likely smokers are to develop the life-threatening illness depends largely on how much they smoke, scientists say.

Dr. Irva Hertz-Picciotto, professor of epidemiology at the UNC-CH School of Public Health, conducted the study with Dr. Jeffrey E. Korte of the International Agency for Research on Cancer in Lyon, France; graduate student Mark R. Schultz and Dr. Louise M. Ball, professor of environmental sciences and engineering, both at UNC-CH; and Dr. Eric J. Duell of Harvard University.

A report on their findings appears in the current (April) issue of the journal Environmental Health Perspectives. They originally intended to help explain why smokers were one-and-a-half to two times more likely to develop the blood-borne cancer than non-smokers and the possible influence of benzene.

"We extrapolated down from different studies that have been done on leukemia and people exposed to benzene in the workplace and established what's called a dose-response curve," Hertz-Picciotto said. "We found that linear mathematical models provided more plausible estimates of benzene's influence than a quadratric model."

Some scientists and industry officials argue that linear models over-estimate the risks at low doses. They say that only at high doses when it overwhelms the body's ability to detoxify the chemical can it cause cancer.

The shape of the dose-response curve is important for the Occupational Safety and Health Administration and Environmental Protection Agency when they attempt to set standards to protect workers and the public. If cancer increases linearly with increases in benzene levels,
'"/>

Contact: David Williamson
david_williamson@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
3-May-2000


Page: 1 2 3

Related biology news :

1. Scientists discover genetic marker responsible for two-fold increase in risk of rheumatoid arthritis
2. Possible link discovered between gene responsible for blood vessel development and ACD in newborns
3. Study of dyslexic brain finds three word forms responsible for reading success
4. Gene mutation responsible for Chrohns disease inflammation identified in Temple study
5. Researchers identify second gene responsible for rare syndrome associated with skeletal defects
6. Specific gene mutations responsible for congenital heart defects
7. Gene responsible for developmental disorder identified
8. Researchers develop guidelines to establish identity of genes responsible for complex diseases
9. Gene responsible for anemia (type CDA-1) discovered
10. Gene responsible for rewinding bodys clock described by scientists at TSRI
11. Researchers find mechanism responsible for neuronal death in prion diseases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/23/2017)... report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), Product ... by MarketsandMarkets, the market is expected to be worth USD 18.98 billion by ... Continue Reading ... ...      (Logo: http://photos.prnewswire.com/prnh/20160303/792302) ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... ... 2017 , ... The award-winning American Farmer television series will feature 3 Bar ... Tuesdays at 8:30aET on RFD-TV. , With global population estimates nearing ten billion ... continue to feed a growing nation. At the same time, many of our valuable ...
(Date:10/9/2017)... Phoenix, Arizona (PRWEB) , ... October 09, 2017 ... ... of Kindred, a four-tiered line of medical marijuana products targeting the needs of ... production and packaging of Kindred takes place in Phoenix, Arizona. , As operators ...
(Date:10/7/2017)... , ... October 06, 2017 ... ... experience providing advanced instruments and applications consulting for microscopy and surface analysis, ... in application consulting, Nanoscience Analytical offers a broad range of contract analysis ...
(Date:10/7/2017)... WALTHAM, Mass. , Oct. 6, 2017 /PRNewswire/ ... pioneering work of three scientists, Jacques Dubochet, ... whose breakthrough developments in cryo-electron microscopy ... this technology within the structural biology community. The ... Scientific. Scientists can now routinely produce highly resolved, ...
Breaking Biology Technology:
Cached News: