HOME >> BIOLOGY >> NEWS
Big-bottomed sheep have a rare genetic mutation that builds muscle, not fat

DURHAM, N.C. -- Scientists have discovered an elusive, mutated gene named for the Greek goddess, Aphrodite Kallipygos, that causes certain sheep to have unusually big and muscular bottoms. They hope the genetic mutation will illuminate how muscle and fat are deposited in these animals and possibly in humans.

The discovery is especially exciting, said the researchers, because the unusual gene has evaded all the traditional means of detection for nearly a decade. In fact, the gene appears to represent one of numerous stealth genes, called "imprinted," that have yet to be discovered but which could produce a wide range of diseases.

Researchers from the U.S. Department of Agriculture and Duke University Medical Center discovered a gene called "callipyge," (pronounced cal - ah - PEEJ) meaning "beautiful buttocks" in Greek, because the sheep have large, muscular bottoms with very little fat. Such an attribute could prove beneficial in breeding these sheep because it enables them to convert food into muscle 30 percent more efficiently than normal sheep. Moreover, the gene could explain specific processes that give rise to obesity and fat metabolism, said Randy Jirtle, Ph.D., professor of radiation oncology at Duke and co-author of the study.

"These sheep are, in effect, pumping iron without lifting weights," explained Jirtle. "They are converting food into muscle in their hind regions, instead of converting food into fat."

Results of the study, funded by the USDA and the National Institutes of Health, are published in the October 2002 issue of Genome Research.

Excited as they are to have unearthed the gene behind the big-bottomed sheep, the scientists say their discovery has equally dramatic implications for mining the human genome. The callipyge gene appears to be among a rare subset that eludes traditional methods of identification and mapping, said USDA geneticist Brad Freking, Ph.D., lead investigator o
'"/>

Contact: Rebecca Levine
levin005@mc.duke.edu
919-684-4148
Duke University Medical Center
16-Sep-2002


Page: 1 2 3 4

Related biology news :

1. Biology behind homosexuality in sheep, study confirms
2. Bighorn sheep threatened by climate change
3. Sport hunting hits evolutionary traits in bighorn sheep
4. Virginia Tech wildlife sciences professor improves sheep counts in Grand Canyon
5. Assessing the risk of mad cow in sheep
6. BSE in sheep: First estimates of human death toll
7. Preventing rapid extinction of bighorn sheep
8. University of Florida researchers test drug from transgenic sheep in study at Shands at UF teaching hospital
9. Researchers determine genetic cause of Timothy syndrome
10. Rare childhood genetic syndrome identified
11. New research shows plants can shuffle and paste gene pieces to generate genetic diversity

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Big bottomed sheep have rare genetic mutation that builds muscle not fat

(Date:3/23/2015)... , March 23, 2015  In the 2014 fiscal ... case conviction losses. This figure accounts for a fraction ... to The Nilson Report, exceeds $11 billion globally. The ... after a crime has occurred. Investor Mark Saint ... expert Joe Paolella partnered to administer the ...
(Date:3/20/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market, announces its biometric payment technology, ... featured in 2015 "I Want That" International CES Special, ... the DIY Network.   DIY,s "I Want ... site of the 2015 International CES for a firsthand ...
(Date:3/17/2015)... , March 17, 2015 ... company specializing in clinical study management systems, is ... in attendance at ARENA,s Outsourcing in Clinical Trials ... This event provides an excellent forum for MedNet ... flexible and affordable software-as-a-service (SaaS) eClinical technology platform. ...
Breaking Biology News(10 mins):Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
(Date:4/23/2015)... 23, 2015 Six startups from ... April 4-17 as part of the U.S.-Russia Innovation ... group of biotechnology startups to participate in the ... (UNN) and the University of Maryland (UMD) signed ... their respective universities in the biomedical industry in ...
(Date:4/23/2015)... 2015  Cryoport, Inc. (OTCBB: CYRX) ("Company"), the ... the life sciences industry, today announced that the ... within the animal husbandry market by signing a ... the shipment of equine semen for artificial insemination ... Animal husbandry is a multi-billion dollar ...
(Date:4/23/2015)... Irvine, CA (PRWEB) April 23, 2015 ... research leader in Personalized Medicine, is excited to ... Medication Response profile . This profile assesses 62 ... and provide dosing information for commonly prescribed non-opioid ... gabapentin (brand name Neurontin), alprazolam (brand name Xanax) ...
(Date:4/23/2015)... ReliantHeart's HeartAssist5® Ventricular Assist Device (VAD) ... the device) in real time, and this data is ... provider of Machine to Machine (M2M) communications for the ... VADLink.com can be monitored by a patient’s ... flow below a minimum threshold, the patient can be ...
Breaking Biology Technology:U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 3U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 4Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Proove Biosciences Launches World’s First Test to Predict Responders to Commonly Prescribed Non-Opioid Pain Medications 2Proove Biosciences Launches World’s First Test to Predict Responders to Commonly Prescribed Non-Opioid Pain Medications 3
Cached News: