Blood markers associated with autism and mental retardation

A new study shows that elevated concentrations of proteins present at birth in the blood may be associated with the development of autism and mental retardation later in childhood. The identification of a biological marker early in life and before the onset of symptoms could lead to earlier and more definitive diagnoses, better clinical definitions, and the discovery of interventional therapies for the disorders. Investigators at the National Institute of Neurological Disorders and Stroke (NINDS), the March of Dimes/California Birth Defects Monitoring Program, and the MIND Institute at the University of California, Davis, collaborated on the study, which will appear in the May 2001 issue of the Annals of Neurology.

The investigators examined and compared archived neonatal blood samples from children, born in four northern California counties from 1983 to 1985, who later developed autism, mental retardation, cerebral palsy, or developed normally. The investigators measured concentrations of several neural growth factors and found that the growth factors were significantly elevated in the neonatal blood of children who later developed autism or mental retardation, but not in the blood from children who developed cerebral palsy or blood from the normal controls.

Finding that major regulators of brain development were different in children with autism from normal controls in the first days of life opens an exciting new avenue of research, says Karin B. Nelson, M.D., Senior Investigator in the Neuroepidemiology Branch of the NINDS. We think this work will be a step to better understanding the biologic basis of autism and hope it will lead to better ways to treat and perhaps prevent autism.

We have these promising new results because the California Department of Health Services had the foresight many years ago to save specimens from the newborn screening program, added study co-author, Judith K. Grether, Ph.D., of the California Department of Health S

Contact: Marcia Vital or Paul Girolami
NIH/National Institute of Neurological Disorders and Stroke

Page: 1 2 3

Related biology news :

1. Blood pressure hormone may inhibit growth of lung cancer
2. Blood tests identify patients on dialysis at high risk for death from cardiovascular disease
3. Blood banking systems improving in China, more progress needed
4. Blood proteins tied to inflammation
5. Bloodworms way with copper likely provides paradigm for new materials
6. Blood markers may reflect newborns potential of contracting HIV
7. Blood stem cells carry targeted genes
8. Blood vessels trigger development of the pancreas
9. Blood vessels found to signal chain of destruction in bone diseases
10. Blood test for diagnosing schizophrenia
11. Blood pressure-lowering DASH diet also reduces homocysteine

Post Your Comments:

(Date:8/26/2020)... ... August 25, 2020 , ... Catalent, the leading global provider ... gene therapies, and consumer health products, today announced that two Catalent Biologics experts ... taking place between Aug. 31 – September 4, 2020. , On Wednesday, Sept. ...
(Date:8/23/2020)... (PRWEB) , ... August 21, 2020 , ... ... Rigaku Corporation has been published and is now available on the company’s ... X-ray diffraction—serves the X-ray analysis community, presenting current news and crystallographic research. ...
(Date:8/21/2020)... ... August 19, 2020 , ... ... SalivaBio LLC, businesses dedicated to Salivary Bioscience for more than twenty years. Together ... book by Springer, " Salivary Bioscience: Foundations of Interdisciplinary Saliva Research and Applications ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine today revealed ... prestigious ranking of the nation’s fastest-growing private companies. The list represents a unique ... independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many other well-known ...
(Date:8/12/2020)... ... August 12, 2020 , ... ... International), a global leader in FDA compliance consulting has been named on its ... companies. The list represents a unique look at the most successful companies within ...
(Date:8/3/2020)... ... 03, 2020 , ... Introducing Ardent Animal Health – MediVet Biologics rebrands company ... Known as MediVet Biologics since its formation in 2016, the company is relaunching ... Health will build on its base of innovative therapies for osteoarthritis and cancer. ...
(Date:7/31/2020)... , ... July 29, 2020 , ... ... solid-state radar transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, ... that can drive one or two switches in a push-pull configuration; yielding fast ...
Breaking Biology Technology:
Cached News: