Blood markers associated with autism and mental retardation

A new study shows that elevated concentrations of proteins present at birth in the blood may be associated with the development of autism and mental retardation later in childhood. The identification of a biological marker early in life and before the onset of symptoms could lead to earlier and more definitive diagnoses, better clinical definitions, and the discovery of interventional therapies for the disorders. Investigators at the National Institute of Neurological Disorders and Stroke (NINDS), the March of Dimes/California Birth Defects Monitoring Program, and the MIND Institute at the University of California, Davis, collaborated on the study, which will appear in the May 2001 issue of the Annals of Neurology.

The investigators examined and compared archived neonatal blood samples from children, born in four northern California counties from 1983 to 1985, who later developed autism, mental retardation, cerebral palsy, or developed normally. The investigators measured concentrations of several neural growth factors and found that the growth factors were significantly elevated in the neonatal blood of children who later developed autism or mental retardation, but not in the blood from children who developed cerebral palsy or blood from the normal controls.

Finding that major regulators of brain development were different in children with autism from normal controls in the first days of life opens an exciting new avenue of research, says Karin B. Nelson, M.D., Senior Investigator in the Neuroepidemiology Branch of the NINDS. We think this work will be a step to better understanding the biologic basis of autism and hope it will lead to better ways to treat and perhaps prevent autism.

We have these promising new results because the California Department of Health Services had the foresight many years ago to save specimens from the newborn screening program, added study co-author, Judith K. Grether, Ph.D., of the California Department of Health S

Contact: Marcia Vital or Paul Girolami
NIH/National Institute of Neurological Disorders and Stroke

Page: 1 2 3

Related biology news :

1. Blood pressure hormone may inhibit growth of lung cancer
2. Blood tests identify patients on dialysis at high risk for death from cardiovascular disease
3. Blood banking systems improving in China, more progress needed
4. Blood proteins tied to inflammation
5. Bloodworms way with copper likely provides paradigm for new materials
6. Blood markers may reflect newborns potential of contracting HIV
7. Blood stem cells carry targeted genes
8. Blood vessels trigger development of the pancreas
9. Blood vessels found to signal chain of destruction in bone diseases
10. Blood test for diagnosing schizophrenia
11. Blood pressure-lowering DASH diet also reduces homocysteine

Post Your Comments:

(Date:7/2/2020)... (PRWEB) , ... July 02, ... ... Biology Systems, B.V. (MBS) has announced a publication detailing the use of ... reverse transcription polymerase chain reaction (RT-PCR) in 16 minutes. The article, titled ...
(Date:7/1/2020)... ... 2020 , ... Cure Glioblastoma, a registered 501(c)(3) nonprofit research ... adult brain cancer—announced today the appointments of its first Senior Fellows: John Boockvar, ... organization’s initiatives and overall vision. , "Senior Fellows are more than advisors; they ...
(Date:6/28/2020)... ... June 25, 2020 , ... In an upcoming episode scheduled for the ... of Care Testing solutions (POCT). Check local listings for more info. , Today, the ... and are shipped to labs throughout the country. Results are then available several days ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... 2020 , ... After research model surgery and catheter implantation, the long journey ... the beginning of a successful study, while protecting and accessing the catheter or device ... of Surgery from Envigo in a live webinar on Wednesday, ...
(Date:7/18/2020)... ... 2020 , ... dicentra , a leading Contract Research ... is pleased to announce that Charles Galea has joined its clinical trials division ... an accomplished and results-driven sales executive with over 10 years of expertise in ...
(Date:7/10/2020)... (PRWEB) , ... July 09, 2020 , ... ... called 1-phenyl-2-thiourea (PTU) is commonly used to suppress pigment formation in zebrafish embryos, ... PolyU research team led by Dr MA has been using the zebrafish model ...
(Date:7/7/2020)... ... July 06, 2020 , ... ... Entries from Roche, Eli Lilly, Bristol-Myers Squibb, the University of Chicago, Massachusetts General ... World has hosted an elite awards program, highlighting outstanding examples of how technology ...
Breaking Biology Technology:
Cached News: