HOME >> BIOLOGY >> NEWS
Blood markers may reflect newborns' potential of contracting HIV

Preventing HIV-infected pregnant women from transmitting the virus to their newborns has long been a major concern for obstetricians. As such, many doctors continue to debate the benefits of elective Caesarian section as a way to protect the infant.

In high-risk pregnancies, where the viral loads can't be suppressed with medication, delivering a baby by C-section directly from the protected, sterile environment of the amniotic sac can limit the risk of HIV transmission. But in lower-risk pregnancies, where antiretroviral medications keep the virus in check, the risk of transmitting HIV to a newborn is only about 1 percent to 2 percent.

A new study by researchers at Johns Hopkins and the National Institutes of Health demonstrates that uncomplicated labor and vaginal delivery does not stimulate the babies' immune systems. Results are scheduled to be presented Jan. 18 at the annual meeting of the Society for Maternal-Fetal Medicine in New Orleans.

A research team led by Hopkins obstetrician Helene Bernstein, M.D., Ph.D., studied lymphocytes from the umbilical cords of 23 babies born by vaginal delivery or elective C-section, as well as cells taken from eight babies born to mothers who had chorioamnionitis (a bacterial infection of the amniotic sac) or preterm labor.

None of the women had HIV. Checking for specific biochemical markers of white blood cell activation, they found the level of cell activity to be similar among babies born by either method. In addition, when HIV was introduced to these cells in the laboratory, there was no difference in their ability to be infected.

However, the babies born to mothers with chorioamnionitis or preterm labor did show activation of their white blood cells. When HIV was introduced to the white blood cells in the laboratory, there were more infections and the virus grew quickly, meaning that these infants could be at higher risk for HIV transmission if born to HIV-infected mothers with
'"/>

Contact: Karen Blum
kblum@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
18-Jan-2002


Page: 1 2

Related biology news :

1. Blood pressure hormone may inhibit growth of lung cancer
2. Blood tests identify patients on dialysis at high risk for death from cardiovascular disease
3. Blood banking systems improving in China, more progress needed
4. Blood proteins tied to inflammation
5. Bloodworms way with copper likely provides paradigm for new materials
6. Blood stem cells carry targeted genes
7. Blood vessels trigger development of the pancreas
8. Blood vessels found to signal chain of destruction in bone diseases
9. Blood markers associated with autism and mental retardation
10. Blood test for diagnosing schizophrenia
11. Blood pressure-lowering DASH diet also reduces homocysteine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/13/2017)... 2017 UBM,s Advanced Design and Manufacturing event ... emerging and evolving technology through its 3D Printing and ... alongside the expo portion of the event and feature ... focused on trending topics within 3D printing and smart ... event will take place June 13-15, 2017 at the Jacob ...
(Date:4/11/2017)... Florida , April 11, 2017 ... a security technology company, announces the appointment of independent Directors ... Bendheim to its Board of Directors, furthering the company,s ... ... of NXT-ID, we look forward to their guidance and benefiting ...
Breaking Biology News(10 mins):
(Date:9/19/2017)... (PRWEB) , ... September 19, 2017 , ... ... a standard fume hood and a high-performance fume hood. Along with the advantages ... and applications for ductless vs. ducted hoods in the laboratory. , Attendees will ...
(Date:9/19/2017)... ... 19, 2017 , ... VetStem Biopharma ’s CEO and founder, Dr. Bob Harman DVM, MPVM, ... book "Stem Cell Therapy: A Rising Tide". Dr. Harman and Dr. Riordan met in ... an interest in the potential of stem cell therapy and a fast friendship was formed. ...
(Date:9/19/2017)... Pleasanton, Calif. and Washington, D.C. (PRWEB) , ... ... ... to delivering rapid care during an biological outbreak is about to be eliminated, ... When asked what makes ExcitePCR’s FireflyDX™ technologies different than other pathogen ...
(Date:9/19/2017)... ... September 19, 2017 , ... Avomeen Analytical ... recipients of its 2017 Science Student Award. The scholarship program is dedicated to ... community service defray the costs of obtaining their science education. , Avomeen began ...
Breaking Biology Technology:
Cached News: