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Blood pressure hormone may inhibit growth of lung cancer

d levels of angiotensin-(1-7)," Tallant and Gallagher said.

The cells for their research came from lung cancers in a 60-year-old female, a 58-year-old male and a 65-year-old male. None of the other angiotensin hormones tested slowed the growth of these lung cancer cells.

Tallant and Gallagher said their studies may point the way to a more successful treatment for lung cancer, still one of the most deadly forms of cancer, with only 13 percent of patients alive after five years.

They said either the administration of angiotensin-(1-7) directly, or through compounds that elevate the angiotensin circulating through the body, such as ACE inhibitors, may both treat and prevent lung cancer, with reduced side effects.

The work was supported by the National Institutes of Health and by a pilot project grant from the Comprehensive Cancer Center of Wake Forest University.


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Contact: Robert Conn
rconn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
30-Jul-2004


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