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Blood stem cells carry targeted genes

oduced fluorescence in all types of the transplanted cells. Four additional control mice without the fluorescent gene showed no fluorescent protein in any transplanted cells.

The researchers will conduct further studies to explore the possibility of delivering genes that boost the immune system to develop stronger therapeutic cancer vaccines. Other possible applications of the technology may be used to suppress the immune system to reduce adult cell transplant rejection. The researchers also will study using this technique to overcome immune system-mediated rejection of embryonic stem cell transplants. No clinical trials are planned at this time.


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Contact: Amy Heaps
heapsam@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
8-Jan-2002


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