HOME >> BIOLOGY >> NEWS
Bone strength probed by scientists

(Santa Barbara, Calif.) The December 13 issue of the journal Nature reports on unique properties of bone revealed in experiments, by scientists at the University of California, Santa Barbara, with the atomic force microscope (AFM).

Collagen, the most abundant protein in the human body serving as a structural component of a variety of tissues including bone, tendon and skin reveals special properties which allow it to "bounce back" when pulled or stressed in laboratory experiments. The AFM operates by tapping and pulling with a tiny needle.

"We learned that the collagen in bone contains sacrificial bonds that rupture as collagen is stretched, and then they reform or heal," said James B. Thompson, first author and a graduate student at UC Santa Barbara.

"These sacrificial bonds provide a mechanism for dissipating mechanical energy in collagen molecules. The time scale required for sacrificial bonds to reform in collagen correlates to the time needed for bone to recover from microscopic indentations."

Besides stretching the collagen from bones, the scientists made small indentations in bone, and like foam rubber that is pressed down, discovered that the bone returns to its original shape. They found that this takes a stiffer force probe, or more force, to indent a bone than to stretch a collagen molecule.

"The surface can recover back to its original shape," said Thompson. "It takes about 30 seconds."

Like the sacrificial bonds in the very tough abalone shell, which has also been studied extensively in the lab of Paul K. Hansma, professor of physics, "these sacrificial bonds found within or between collagen molecules may be partially responsible for the toughness of bone," according to the article.

The article also states that "The longer the delay before the next pull, the more energy dissipation observed when pulling the collagen molecule(s) again."

For the stretch experiments the group used purified cow tendon, and
'"/>

Contact: Gail Brown
gail.brown@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
13-Dec-2001


Page: 1 2

Related biology news :

1. Invention could improve PVC safety and strengthen $1.8-billion industry worldwide
2. Grant from GE Foundation to University of Houston to strengthen math, tech pipeline
3. Researchers reveal calcium transport protein function that regulates heartbeat frequency, strength
4. Tufts University bioengineers discover secret of spider, silkworm fiber strength
5. Swimming can contribute to rebuilding bone strength
6. Grant strengthens research arm of Penn State Hershey Medical Centers ALS Clinic
7. Hebrew University excavations strengthen dating of archaeological findings to David, Solomon
8. Study says: whey to greater muscle strength is through training and protein supplements
9. New NSF institutes to strengthen mathematics as base for national S&T
10. Studies of spiders silk reveal unusual strength
11. Studying the strength of protein bonds one molecule at a time

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... SAN FRANCISCO and BANGALORE, India ... part of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... service provider, today announced a global partnership that ... convenient way to use mobile banking and payment services. ... Mobility is a key innovation area for financial services, but ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
(Date:4/15/2016)... April 15, 2016 Research ... Gait Biometrics Market 2016-2020,"  report to their offering.  ... ) , ,The global gait biometrics market is ... during the period 2016-2020. Gait analysis ... can be used to compute factors that are ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... on what they believe could be a new and helpful biomarker for malignant ... Click here to read it now. , Biomarkers are components in ...
(Date:6/27/2016)...  Liquid Biotech USA , ... Sponsored Research Agreement with The University of Pennsylvania ... cancer patients.  The funding will be used to ... clinical outcomes in cancer patients undergoing a variety ... employed to support the design of a therapeutic, ...
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial ... Cary 5000 and the 6000i models are higher end machines that use the more ... the spectrophotometer’s light beam from the bottom of the cuvette holder. , FireflySci ...
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
Breaking Biology Technology:
Cached News: