HOME >> BIOLOGY >> NEWS
Botanical Products Act Like Estrogen In Animals, Finds University Of Pittsburgh Team

PITTSBURGH, April 11 -- A University of Pittsburgh and Pittsburgh VA Medical Center team has provided new evidence that certain botanical products act like estrogen in animals. The findings indicate how these agents may work to relieve menopausal symptoms but suggest their potential danger for women who should not take estrogen. The scientists are reporting their findings April 11 at the annual meeting of the American Association for Cancer Research in Philadelphia.

"Of the plant products we examined, we found that vitex, dang gui, American ginseng and cohosh produced estrogen-like effects in animals," remarked Patricia Eagon, Ph.D., associate professor of medicine at the University of Pittsburgh and principal investigator on the study. "These findings confirm reports that these plants relieve menopausal symptoms, especially hot flashes. However, we still need to conduct further pre-clinical tests with these substances to study their long-term effects and to ensure that they are safe to use."

"Our results should signal a strong note of caution to women who want to relieve menopausal symptoms but who have a family or personal history of breast or uterine cancer," added Dr. Eagon. Estrogen is known to fuel the growth of these cancers.

Because the U.S. Food and Drug Administration does not regulate these botanical products, many women who should not take them could end up using them, remarked Dr. Eagon. Moreover, overuse of these remedies or impurities in the products can lead to liver problems and blood clotting disorders, she added.

The Pittsburgh research team found that extracts of vitex, dang gui, American ginseng and cohosh bound directly to estrogen receptors, just as natural estrogen would. The investigators next tested these compounds in rats whose ovaries were removed so they could not produce significant levels of natural estrogen. After 30 days of treatment, the researchers found that the uterus in each rat grew heavier, an indic
'"/>

Contact: Lauren Ward
wardle@msx.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
11-Apr-1999


Page: 1 2

Related biology news :

1. Botanical evidence indicates "Shroud of Turin" originated in Jerusalem area before 8th century
2. XVI International Botanical Congress tentative media briefing schedule
3. New Polyester Products Perform Better And Are Easy To Recycle
4. Formaldehyde Emissions From Consumer Products
5. Turning "Unrecyclable" Waste Into Plastic Products
6. Photosynthetic Harvest Inc. Harnesses The Power Of Natures Chemical Factories By "Milking" Green Plants For Valuable Natural Products
7. Health Effects Of Consuming Alcohol, Dairy Foods, And Iron-Fortified Products ToBe Debated
8. Component In Soy Products May Be Substitute For Estrogen Treatment
9. Estrogen promotes gender differences in brains response to stress
10. Estrogen receptor-a disruption and vasodilation in coronary arteries
11. Estrogen improves short term memory and oral reading in midlife postmenopausal women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... , ... Regenative Labs has received approval from the Centers for Medicare & ... first Wharton’s jelly allografts to be assigned a Q code and be approved for ... Wharton’s jelly allograft product to be recognized as a 361 HCT/P by CMS regulated ...
(Date:7/18/2020)... ... July 16, 2020 , ... A study has been published ... Neoasis™ active noise control device to attenuate typical noises in a simulated neonatal ... the alarm sounds from patient monitors, ventilators and other bedside devices that would ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. http://www.altrubio.com ... a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European ... J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... FARMS, Mich. (PRWEB) , ... August 12, 2020 ... ... Consulting Group, Inc. (EMMA International), a global leader in FDA compliance consulting ... of the nation’s fastest-growing private companies. The list represents a unique look at ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... collection, today announced Jim Corrigan, President and CEO has been named one of ... broad cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International is ... $3950. With 50 million stem cells total, patients may choose which extremities they would ... for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue is ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
Breaking Biology Technology:
Cached News: