HOME >> BIOLOGY >> NEWS
Breast fluid a better option for detecting cancer

RICHLAND, Wash. - A new method of extracting and analyzing fluid from a woman's breast may provide a more accurate, less expensive and noninvasive way to determine a patient's risk for breast cancer or to diagnose the disease in its early stages.

In a paper published in the July 3 issue of Breast Cancer Research and Treatment, Battelle scientists at the Department of Energy's Pacific Northwest National Laboratory and researchers at University of California, Los Angeles report they have discovered six times more proteins than previously identified in this fluid, called nipple aspirate fluid, or NAF. The presence of such proteins suggests that NAF could be a resource for biomarkers, or biological indicators, of breast cancer, which is expected to claim the lives of approximately 40,000 American women this year.

"We believe this fluid could be the best alternative for discovering biomarkers for early-stage breast cancer," said Rick Zangar, a Battelle principal investigator at PNNL. "With further analysis, we could detect up to 10 times more proteins in NAF. The more proteins we identify, the better chance there is to find one that is linked to breast cancer."

Proteins can serve as biomarkers of disease. When cancerous cells begin to develop, they create their own proteins that, if detected in NAF, could indicate the presence or risk of breast cancer. Current methods for screening include breast self-exams and mammograms, which are physical exams compared with the molecular approach at PNNL.

NAF is continuously secreted and reabsorbed in breasts of women who aren't pregnant or lactating. It is generated from cells lining the ducts that form a network throughout the breast, the same network that provides milk in a lactating woman. These ductal cells are the source of 70 to 80 percent of breast cancer.

"NAF offers a unique window through which we can monitor the processes occurring inside the breast ductal system," Zangar said
'"/>

Contact: Staci Maloof
staci.maloof@pnl.gov
509-372-6313
DOE/Pacific Northwest National Laboratory
8-Jul-2003


Page: 1 2 3

Related biology news :

1. Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
2. Breastfeeding decreases infant mortality
3. Breast cancer study suggests role for tissue in carcinogenesis
4. Breast self examination increases womens concerns but has no effect on mortality
5. Breast cancer follow-ups no longer guess-work thanks to new physics research
6. Final media advisory for the 4th European Breast Cancer Conference (EBCC-4)
7. The 4th European Breast Cancer Conference (EBCC4)
8. Breast cancer susceptibility genes play role in DNA repair
9. Breast cancer can be reversed in laboratory mice, scientists report
10. NIH funds Breast Cancer and the Environmental Research Center at Fox Chase Cancer Center
11. Breastfeeding may compensate for harmful effects of smoking during pregnancy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... CHICAGO (PRWEB) , ... July 09, 2020 , ... Today ... Umami Advantage, which will share insight on the “fifth taste” phenomenon that is revolutionizing ... snacks. The Umami Advantage will be live on Monday, July 13, 2020 at11:00 AM ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. ... of Neihulizumab, a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), ... Dr. Paul J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, ...
(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, a global leader ... Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga prefecture of Japan. ... in Kakegawa, the new 60,000-square-foot facility will provide customers with flexible clinical supply ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... July 16, 2020 , ... After research model surgery and ... a great surgery is only the beginning of a successful study, while protecting and ... Join Brad Gien, Global Head of Surgery from Envigo in a ...
(Date:7/10/2020)... ... July 08, 2020 , ... Bode Technology, ... expansion of laboratory operations through its COVID-19 testing service, Bode-CARES . Bode-CARES ... , Bode-CARES provides a turnkey solution that includes a comprehensive collection ...
(Date:7/7/2020)... ... 06, 2020 , ... R3 International is now offering stem cell therapy for ... cells. Depending on the patient's condition, treatment may be offered IV, intrathecal or with ... form of Alzheimers dementia, and the incidence continues to increase as individuals live longer. ...
(Date:7/1/2020)... , ... June 30, 2020 ... ... tissue data insights, today announced that the launch of a new ... with data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is a ...
Breaking Biology Technology:
Cached News: