HOME >> BIOLOGY >> NEWS
Breast fluid a better option for detecting cancer

. "The medical community recognizes that one way to markedly decrease mortality from breast cancer would be a more accurate, noninvasive method for early diagnosis. Our approach suggests there could be other options available."

The NAF samples were collected using an enhanced process that is less painful than other extraction methods yet obtains just as much fluid. It was developed by co-author Chandice Covington, Professor and Chair, Primary Care Nursing at UCLA School of Nursing.

While NAF has been studied for more than 25 years, most extraction methods have been painful. Through Covington's process, women use warmth, massage and a simple breast pump that eases the fluid from the breast without discomfort.

"Women need early mechanisms for detecting potential or existing disease," Covington said. "Current detection methods rely on feeling a lump in a self-exam or visualizing a lump in a mammogram. By the time a lump has formed, the cancer has progressed. My technique, combined with Battelle's protein analysis capabilities, makes our approach one of the leading methods for identifying biomarkers for breast cancer in the early stages, before a lump is detectable."

Zangar and colleague Susan Varnum analyzed the NAF samples using high-throughput mass spectrometers located in the William R. Wiley Environmental Molecular Sciences Laboratory, a DOE national user facility located at PNNL. Of the 65 proteins identified, 15 of them, or 23 percent, have been previously implicated as potential biomarkers for breast cancer. This implies that NAF provides a useful sample for analysis of known breast cancer biomarkers, while offering the possibility of providing novel biomarkers not yet identified in blood samples.

The results are promising, but Zangar also noted there are more questions that need to be addressed.

"Will a biomarker show up sooner in NAF than in blood? We don't know yet, but we do know that NAF is a concent
'"/>

Contact: Staci Maloof
staci.maloof@pnl.gov
509-372-6313
DOE/Pacific Northwest National Laboratory
8-Jul-2003


Page: 1 2 3

Related biology news :

1. Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
2. Breastfeeding decreases infant mortality
3. Breast cancer study suggests role for tissue in carcinogenesis
4. Breast self examination increases womens concerns but has no effect on mortality
5. Breast cancer follow-ups no longer guess-work thanks to new physics research
6. Final media advisory for the 4th European Breast Cancer Conference (EBCC-4)
7. The 4th European Breast Cancer Conference (EBCC4)
8. Breast cancer susceptibility genes play role in DNA repair
9. Breast cancer can be reversed in laboratory mice, scientists report
10. NIH funds Breast Cancer and the Environmental Research Center at Fox Chase Cancer Center
11. Breastfeeding may compensate for harmful effects of smoking during pregnancy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/3/2020)... ... , ... Amplify Surgical, Inc., today announces that the company reached the milestone ... , The landmark case was performed by Dr. Ali Najafi at Fresno Heart and ... completely changed the game for expandable interbodies. The ability to achieve an ALIF ...
(Date:3/2/2020)... ... ... Toronto-based clinical research organization (CRO) and regulatory consulting firm, dicentra , has announced ... Clarksburg on a farm on Beaver Valley Road. , The owners currently operate an ... it would be a great new option for employees to relocate to. , “Part ...
(Date:3/2/2020)... (PRWEB) , ... March 02, 2020 , ... Nominations are ... program co-founded by the Security Industry Association (SIA) and SecureIDNews ... SIA Women in Security Forum . The recipients of this year’s Women in Biometrics ...
Breaking Biology News(10 mins):
(Date:3/3/2020)... ... March 03, 2020 , ... Frictionless Solutions, a ... device industries, was recognized by INC. 5,000 on an annual list of America’s ... industry leaders greatly impacting their spheres of influence and experiencing considerable development. INC. ...
(Date:3/2/2020)... ... ... McBee, Moore and Vanik IP, LLC (MMV IP) has been ranked 12th ... , According to statistics compiled by Harrity Anaytics, MMV IP was listed as the ... during 2019. Technology center 1600 at the US Patent Office (“USPTO”) specializes in the ...
(Date:2/26/2020)... ... February 25, 2020 , ... Continuing its leading research ... results of its safety assessment on the biotechnologically produced 3-Fucolsyllactose (3-FL) HMO. ... These complex carbohydrates are indigestible and therefore function as a prebiotic by promoting ...
(Date:2/21/2020)... ... February 20, 2020 , ... ... efficient and elegant chemistry. Humans have been increasingly successful in innovating ways ... Through rapidly evolving technologies and strategies for modern molecular biology (e.g., gene ...
Breaking Biology Technology:
Cached News: