HOME >> BIOLOGY >> NEWS
Bright idea could doom cancer and viruses, say Purdue scientists

WEST LAFAYETTE, Ind. - Cancer and viruses may someday find themselves blinded by the light of therapies based on recent Purdue University chemistry research.

A team of scientists including Harry Morrison has developed a group of rhodium-based compounds that, when exposed to light, can kill tumor cells and deactivate a virus closely related to the West Nile and yellow fever viruses. Unlike the ordinary substances used for chemotherapy, these chemicals are not harmful to the body in general - they only become lethal to DNA when activated by light of a specific frequency. While therapies based on the discovery are likely many years away, the compounds could have potential as anticancer agents and for blood sterilization.

"We have proven in principle that light and chemistry together can destroy tumor cells and the Sindbis virus, a member of a group of viruses that cause encephalitis, fever and arthritis," said Morrison, who is professor of chemistry and former dean of Purdue's School of Science. "This research offers hope that someday we may be able to replace standard chemotherapy drugs with others that are far less generally harmful to a patient's body and guarantee safe, sterile blood for transfusions."

The research, which appears in the current (Aug. 23) issue of Inorganic Chemistry, was conducted by lead author Elton L. Menon along with Rushika Perera, Richard J. Kuhn and Morrison, all of Purdue, and Maribel Navarro of the Instituto Venezolano de Investigaciones Cientificas, Venezuela.

Chemotherapy has long made use of platinum-based compounds to poison cancer cells. These compounds bind DNA in the cellular nucleus and render the cell unable to reproduce, effectively destroying it. The trouble is, such chemicals also kill many other healthy cells in the body in the process.

"That's the reason cancer patients often lose their hair," Morrison said. "Hair cells, like many others in the patient's body, are also destr
'"/>

Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
24-Aug-2004


Page: 1 2 3

Related biology news :

1. Brightness discrimination in the dog
2. Bright autumn colouration in trees - a warning signal to insects?
3. Bright beaks provide honest look at male immune system, Science study says
4. New Device Brightens Recycling Efforts
5. Testing Sought For Brighteners, Natural Substance In Spices, Cosmetic Chemical, Three Herbs, A Natural Oil And A Fertilizer
6. Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
7. Circulation of disaster myths in Haiti could hinder appropriate disposal of bodies
8. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
9. Marijuana use could cause tubal pregnancies
10. Gene chips research in cotton could lead to superior variety
11. Groundbreaking research could ignite new solutions to heat transfer in nano-devices

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2020)... Calif. (PRWEB) , ... August 19, 2020 , ... ... both Salimetrics LLC and SalivaBio LLC, businesses dedicated to Salivary Bioscience for more ... of the recently published book by Springer, " Salivary Bioscience: Foundations of Interdisciplinary ...
(Date:8/12/2020)... ... 2020 , ... Mosio recently announced its newly updated text ... of all sizes. With a focus on tracking symptoms and monitoring outbreaks as ... Mosio helps public health departments automate communications and provide more personalized care and ...
(Date:8/3/2020)... ... 03, 2020 , ... Accumen Inc. is helping healthcare get ... Spectrum Solutions, to provide COVID-19 saliva testing kits nationally. , “Accumen has ... than 10 years. Early in the COVID-19 crisis, we identified supply chain gaps ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... ... True Terpenes , the leading platform for terpene innovation, research and development, ... medical potential of terpenes and the potential entourage effect , where the benefits ... on expanding the recently launched line of effects-based terpenes - Terpology by Dr. ...
(Date:8/12/2020)... ... August 11, 2020 , ... ... available for free its new white paper – Simulated Transport Methodologies. Regulatory ... today’s biologics licensing application (BLA). In response, Modality Solutions shares an explanation ...
(Date:8/3/2020)... ... 03, 2020 , ... ERT, the global leader ... been named one of the 100 most inspiring individuals in the life-sciences industry ... selected based on how they have inspired their colleagues and affected positive changes ...
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON Manufacturing, the leader ... tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes at a time ... track capacity to provide patients with urgently needed vaccines and other lifesaving pharmaceutical ...
Breaking Biology Technology:
Cached News: