CAK Activation Of Plant Cell Cycle: Scientists Find Another Piece In The Jigsaw Puzzle To Help Explain Why Plants Do Not Develop Cancer Spontaneously

Cancer cells proliferate uncontrolled, so regulation of the entry into the cell division cycle by external hormonal and stress stimuli is a central theme of cancer research. In contrast to animals, plants appear to have strong preventive mechanisms to avoid this kind of uncontrolled cell division. On the other hand, and unlike animal cells, plant cells that fulfill specific functions and are therefore differentiated are able to reactivate cell division. This is the reason why it is possible to regenerate new plants from individual cells in tissue culture. However, because of the differences between plants and animals, the identification of functions regulating the plant cell cycle may provide an important lesson about how evolutionary changes have led to less rigorous control of cell proliferation in mammals.

In all eukaryotes, the cell cycle is regulated by enzymes called cyclin-dependent protein kinases (CDKs). Plants harbour several different CDKs that are all related to their yeast and animal counterpart. Activation of the cell cycle at various control points requires the phosphorylation of CDKs by CDK-activating kinases (CAKs) that represent important targets within cellular signaling pathways. Two major types of CAKs have so far been identified. One type establishes contact with the machinery necessary to provide the template (messenger RNA) to produce proteins within a cell according to the DNA blueprint. This machinery is called the transcriptional apparatus and contains an enzyme called RNA polymerase II complex, which is necessary to produce the messenger RNA. These CAKs, known from animals and fission yeasts, make contact to a particular part of a subunit of the RNA polymerase II complex. The

Contact: Csaba Koncz

Page: 1 2 3

Related biology news :

1. Activation of receptor ups development of precancerous intestinal polyps
2. Scientists Discover New Players On The Gene-Activation Team
3. Researchers Identify A Protein Critical For T Cell Development And Activation
4. New Finding Suggests "HATs" Are Key To Gene Activation Puzzle
5. Plants will not save us from greenhouse gases
6. Plant pathologists meeting in Anaheim, CA to discuss agricultural security, food safety, and more
7. Plant gene discovery could enhance plant growth, reduce fertilizer needs and phosphate pollution
8. Plant respiration not just an evolutionary leftover, study shows
9. Canadian Society of Agronomy partners with Plant Management Network
10. Plant pathologists look to forensics to aid in biosecurity
11. Plants for the future: A European vision for plant biotechnology towards 2025

Post Your Comments:

(Date:8/5/2020)... ... , ... Regenative Labs has received approval from the Centers for Medicare & ... first Wharton’s jelly allografts to be assigned a Q code and be approved for ... Wharton’s jelly allograft product to be recognized as a 361 HCT/P by CMS regulated ...
(Date:7/18/2020)... ... July 16, 2020 , ... A study has been published ... Neoasis™ active noise control device to attenuate typical noises in a simulated neonatal ... the alarm sounds from patient monitors, ventilators and other bedside devices that would ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. http://www.altrubio.com ... a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European ... J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... FARMS, Mich. (PRWEB) , ... August 12, 2020 ... ... Consulting Group, Inc. (EMMA International), a global leader in FDA compliance consulting ... of the nation’s fastest-growing private companies. The list represents a unique look at ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... collection, today announced Jim Corrigan, President and CEO has been named one of ... broad cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International is ... $3950. With 50 million stem cells total, patients may choose which extremities they would ... for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue is ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
Breaking Biology Technology:
Cached News: