The interdisciplinary nature of the program is demonstrated by the center having equal co-directors: Yoh-Han Pao, the George S. Dively Distinguished Professor Emeritus of Engineering from the School of Engineering, and Joe Nadeau, the James H. Jewell, M.D., Med '34 Professor in Genetics from the School of Medicine.

"With the recent reports of the human genome sequence and that of the mouse, research attention now shifts from questions of gene sequence and genome content to problems of protein function and how proteins regulate the biology of the organism," said Nadeau.

"These are hard, challenging and important problems. Their solution requires a novel combination of traditional basic research together with genomics approaches. Underlying all of the wet-lab research is strong research and training programs in computational genomics and bioinformatics, both to manage and analyze the new information about genes and functions in health and disease, but also to understand how genes function individually and collectively to elaborate organismal biology in health and disease."

Pao said, "The center will foster excellence and creativity in computational genomics research. The research issues will include questions of structure and function, and this is where powerful computational analysis, learning and inference capabilities play important roles in this research. We know that CWRU is deeply committed to genetics and bioinformatics research and we intend to play a significant part in that activity. We have good relationships with other such research activities at universities and businesses, and will maintain these and strengt
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Contact: George Stamatis
gxs18@po.cwru.edu
216-368-3635
Case Western Reserve University
8-Aug-2001