HOME >> BIOLOGY >> NEWS
Calcium supplements associated with decreased risk of large bowel polyps

Taking calcium supplements is associated with a decreased risk of advanced colon polyps, according to a new study published in the June 16 issue of the Journal of the National Cancer Institute.

Although high calcium intake has been shown to inhibit colon cancer in animal experiments, these effects have not been seen consistently in human studies. In addition, the few studies that have demonstrated an association between calcium intake and moderate decreases in the risk of precancerous colorectal tumors have rarely evaluated the effect of calcium on different types of colorectal lesions or how other aspects of diet may alter the effects of calcium.

To explore in greater detail the chemopreventive effects of calcium supplementation, Kristin Wallace, M.S., and John A. Baron, M.D., of the Dartmouth Medical School in Lebanon, N.H., and colleagues analyzed data from 913 patients enrolled in the Calcium Polyp Prevention Study, a randomized, double-blind, placebo-controlled trial. Patients took either a 1200 mg calcium supplement or a placebo and had a follow-up colonoscopy 1 and 4 years after enrolling in the trial.

Supplemental calcium slightly decreased the risk of all types of colorectal polyps. The effect was greatest for the advanced lesions that are felt to be most strongly associated with invasive colorectal cancer. In addition, there was some evidence that a diet high in fiber and low in fat increased the preventive effect of calcium, but these results were not statistically definitive.

These findings "suggest that total calcium intakes above 1200 mg are necessary, and perhaps that high dietary fiber and modest dietary fat are required to optimize this [anticancer] effect. Additional data regarding nutrient interactions with calcium will help further refine optimum cancer protective strategies and may clarify the mechanisms by which calcium has its effects in the large bowel," the authors write.

In an editorial, Arthu
'"/>

Contact: Sarah L. Zielinski
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
15-Jun-2004


Page: 1 2

Related biology news :

1. Calcium channels control coronary artery relaxation
2. Calcium channel involved in coronary artery relaxation
3. Calcium signals found to guide nerve cell development
4. Calcium and Lead: should you worry?
5. Calcium absorption is not affected by a high protein diet
6. Calcium is not as readily absorbed from soy milk as from cows milk
7. Calcium not the only key to bone health in older women
8. Purdue Study: Calcium May Curb Weight Gain In Young Women
9. Trees Need Calcium Too
10. New England Journal Of Medicine Reports Calcium Supplements Help Prevent Polyp Recurrence; DMS Led Study
11. Study: Calcium Supplements Appear To Protect Against Colorectal Cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2019)... ... 2019 , ... Serialization deadlines in the US and European ... aggregation becomes fully applied in the United States in 2023, pharmaceutical companies are ... now, most regulations?including the Drug Supply Chain Security Act (DSCSA)?have required minimal system ...
(Date:8/14/2019)... ... 14, 2019 , ... Representatives with MyBioGate announced that China Focus@Biotech Week will ... “We help innovative projects connect with Chinese pharma and investors in healthcare innovation,” said ... to explain that as a part of Biotech Week Boston – the annual biotech ...
(Date:8/6/2019)... ... August 06, 2019 , ... A study released today ... have far-reaching implications for personalized medicine, especially when seeking treatments for children with ... predict which stem cell donors and manipulation methods might yield the best therapies ...
Breaking Biology News(10 mins):
(Date:7/11/2019)... ... July 11, 2019 , ... At the most recent stem ... to eight military Veterans under the R3 Heroes Program. The Veterans included individuals and ... Heroes Program allow anyone to nominate a military Veteran, teacher or first responder to ...
(Date:7/9/2019)... , ... July 08, 2019 , ... ... The company’s SmartLight Indicator was recognized as the 2019 Innovative Product of the ... forward. The prestigious awards were during Sensors Expo & Conference 2019, ...
(Date:6/26/2019)... ... June 26, 2019 , ... Alice Branton today released research results ... properties of Magnesium Gluconate, which can prove to be beneficial for treating Hypomagnesemia. , ... differentiation peak, change in crystallite size , Over 142% increase in particle ...
(Date:6/18/2019)... ... ... Personalized Stem Cells, Inc (“PSC”), a human adipose-derived stem cell company, ... a person’s own adipose-derived stem cells to treat their osteoarthritis. The first clinical trial ... is the first of several planned clinical trials which will enable qualified PSC-enrolled physicians ...
Breaking Biology Technology:
Cached News: