HOME >> BIOLOGY >> NEWS
Calcium supplements associated with decreased risk of large bowel polyps

Taking calcium supplements is associated with a decreased risk of advanced colon polyps, according to a new study published in the June 16 issue of the Journal of the National Cancer Institute.

Although high calcium intake has been shown to inhibit colon cancer in animal experiments, these effects have not been seen consistently in human studies. In addition, the few studies that have demonstrated an association between calcium intake and moderate decreases in the risk of precancerous colorectal tumors have rarely evaluated the effect of calcium on different types of colorectal lesions or how other aspects of diet may alter the effects of calcium.

To explore in greater detail the chemopreventive effects of calcium supplementation, Kristin Wallace, M.S., and John A. Baron, M.D., of the Dartmouth Medical School in Lebanon, N.H., and colleagues analyzed data from 913 patients enrolled in the Calcium Polyp Prevention Study, a randomized, double-blind, placebo-controlled trial. Patients took either a 1200 mg calcium supplement or a placebo and had a follow-up colonoscopy 1 and 4 years after enrolling in the trial.

Supplemental calcium slightly decreased the risk of all types of colorectal polyps. The effect was greatest for the advanced lesions that are felt to be most strongly associated with invasive colorectal cancer. In addition, there was some evidence that a diet high in fiber and low in fat increased the preventive effect of calcium, but these results were not statistically definitive.

These findings "suggest that total calcium intakes above 1200 mg are necessary, and perhaps that high dietary fiber and modest dietary fat are required to optimize this [anticancer] effect. Additional data regarding nutrient interactions with calcium will help further refine optimum cancer protective strategies and may clarify the mechanisms by which calcium has its effects in the large bowel," the authors write.

In an editorial, Arthu
'"/>

Contact: Sarah L. Zielinski
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
15-Jun-2004


Page: 1 2

Related biology news :

1. Calcium channels control coronary artery relaxation
2. Calcium channel involved in coronary artery relaxation
3. Calcium signals found to guide nerve cell development
4. Calcium and Lead: should you worry?
5. Calcium absorption is not affected by a high protein diet
6. Calcium is not as readily absorbed from soy milk as from cows milk
7. Calcium not the only key to bone health in older women
8. Purdue Study: Calcium May Curb Weight Gain In Young Women
9. Trees Need Calcium Too
10. New England Journal Of Medicine Reports Calcium Supplements Help Prevent Polyp Recurrence; DMS Led Study
11. Study: Calcium Supplements Appear To Protect Against Colorectal Cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... July 02, 2020 , ... ... a publication detailing the use of its revolutionary NEXTGENPCR endpoint thermocycler to ... in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR protocol for the ...
(Date:6/28/2020)... BASEL, Switzerland (PRWEB) , ... ... ... leading provider of enterprise software solutions for biopharmaceutical R&D, today announced that ... oncology company developing innovative, full-length multispecific antibodies (Multiclonics®), to support their translational ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... gene-to-protein and monoclonal antibody development services, today announced that the company has ... services to the pharmaceutical, diagnostics, and research industries. The decision to pursue ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... ... July 09, 2020 , ... In most ... used to suppress pigment formation in zebrafish embryos, maintaining optical transparency to facilitate ... Dr MA has been using the zebrafish model to investigate the causes of ...
(Date:7/7/2020)... ... 2020 , ... R3 International is now offering stem cell therapy for Alzheimers ... Depending on the patient's condition, treatment may be offered IV, intrathecal or with a ... of Alzheimers dementia, and the incidence continues to increase as individuals live longer. There ...
(Date:7/1/2020)... (PRWEB) , ... June 29, 2020 , ... ... year to date growth of 40% in 2020, despite many obstacles created as ... MedShift aims to increase revenue for its partnered medical practices and medical manufacturers ...
(Date:7/1/2020)... ... June 30, 2020 , ... Flagship ... of a new clinical diagnostics immuno-oncology service, TissueInsight . TissueInsight provides ... “Flagship’s TissueInsight is a service that aids pathologists, oncologists, and immunologists in ...
Breaking Biology Technology:
Cached News: