Californian wins neuroscience prize endowed by UNC scientist

CHAPEL HILL - A California researcher became the first winner of an annual national prize endowed by a distinguished scientist at the University of North Carolina. The prize is for an outstanding scientific contribution to the field of neuroscience.

The $10,000 Perl-UNC Neuroscience Prize, announced last week, goes to David Julius, PhD, professor of cellular and molecular pharmacology at the University of California San Francisco School of Medicine.

Julius discovered the nerve cell molecule that mediates responses to capsaicin, the active ingredient in hot peppers. The capsaicin receptor, VR1, is also responsible for the transmission of noxious heat sensations.

That discovery four years ago, and Julius' subsequent studies, build on the pioneering research of neurophysiologist Edward R. Perl, M.D., Sarah Graham Kenan Professor of Cell and Molecular Physiology at UNC-CH School of Medicine. Perl's work in pain mechanisms has been highly influential. Thirty years ago, he was the first to prove that a particular class of nerve cells (now called nociceptors) respond exclusively to stimuli that we perceive as painful. His work has had a decisive impact on modern pain research and these cells are now targets of intensive efforts to find drugs that block their function.

"Although Ed showed that a class of sensory neurons respond exclusively to painful stimuli, no molecules had been identified that provide the basis for how those neurons were able to do that," said William Snider, MD, director of the Neuroscience Center at UNC and head of the selection committee for the Prize.

"And people had known that capsaicin applied to sensory neurons causes them to be electrically active. Yet attempts to identify, clone or purify a receptor for this ingredient had failed. David Julius, using an ingenious assay system and sophisticated molecular techniques, was able to clone the gene encoding this receptor. Remarkably, it then turned out that the receptor also

Contact: Leslie H. Lang
University of North Carolina School of Medicine

Page: 1 2

Related biology news :

1. Southern Californians commonly misinformed about beach water quality, study finds
2. Discoveries in neuroscience
3. Seattle, New York researchers to receive neuroscience prize endowed by UNC scientist
4. UNC neuroscience center awarded $1.7 million for nerve growth and regeneration studies
5. Brown engineering and neuroscience group wins grant for brain study
6. UB biophysicist receives $2.7 million Jacob Javits award to continue distinguished research in neuroscience
7. National prize in neuroscience endowed by UNC professor
8. March of Dimes awards $250,000 prize to pioneering scientist
9. Heinz Maier-Leibnitz prizes 2004
10. Structure of a Nobel-prize winning molecule: Aquaporin
11. Hebrew University Ph.D. graduate wins young scientist prize in US

Post Your Comments:

(Date:6/5/2020)... ... June 04, 2020 , ... Murrieta Genomics has announced that its ... simplified sample preparation for Next Generation Genomic Sequencing (NGS) . This is the ... complexity of sample preparation. , “I have been at the bench for over 20 ...
(Date:6/2/2020)... ... June 02, 2020 , ... ... software developer and solutions provider, today reported that the implementation of browser-based, ... compliance by 100%, resulting in greater efficiency for global biotechnology company, bioMérieux. ...
(Date:5/28/2020)... ... May 27, 2020 , ... ... Workforce Advisor™ , a solution that uniquely combines lab testing insights and hc1’s ... systematically support the ongoing health and safety of employees returning to the workplace. ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... July 16, 2020 , ... ... in the early detection and prevention of high-burden diseases, and Centric Consulting, a ... and healthcare organizations to utilize existing data in order to identify and prioritize ...
(Date:7/10/2020)... ... July 09, 2020 , ... In most ... used to suppress pigment formation in zebrafish embryos, maintaining optical transparency to facilitate ... Dr MA has been using the zebrafish model to investigate the causes of ...
(Date:7/1/2020)... CHARLOTTE, N.C. (PRWEB) , ... June 29, 2020 ... ... has reported year to date growth of 40% in 2020, despite many obstacles ... medical technology, MedShift aims to increase revenue for its partnered medical practices and ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... to develop a vaccine or drug treatment. In an effort to better understand ... publicly released the world’s largest imaging dataset portraying therapeutic compound effects from over ...
Breaking Biology Technology:
Cached News: